Medical Microbiology and parasitology- Scholarly Publications

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Browsing Medical Microbiology and parasitology- Scholarly Publications by Author "Aboderin, A.O."

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    A point prevalence survey of antimicrobial prescribing in four nigerian tertiary hospitals
    (Wolters kluwer - medknow42, 2017) Oduyebo, O.O.; Olayinka, A.T.; Iregbu, K.C.; Versporten, A.; Goossens, H.; Nwajiobi-princewill, P.I.; Jimoh, O.; Ige, T.O.; Aigbe, A.I.; Ola-bello, O.I.; Aboderin, A.O.; Ogunsola, F.T.
    Antimicrobial resistance has become a global challenge in health care. Its emergence in previously sensitive bacteria is usually associated with poor antibiotic-prescribing patterns. Methodology: A point prevalence survey was carried out in four tertiary hospitals in Nigeria in 2015 to determine the rate and characteristics of antibiotic prescription. Results: Of 828 patients eligible for the study, 69.7% received antibiotics, with highest rates in the adult Intensive Care Unit. There were therapeutic indications in 51.2% of the prescriptions, of which 89.5% were for community-acquired infections. Third-generation cephalosporins were the most prescribed antibiotics. On the evaluation of surgical prophylaxis, only 4.1% were compliant with institutional guidelines and 39.2% gave a reason for prescribing in patient case notes. Less than 1% of the prescriptions were based on the use of biomarkers. Conclusion: The prevalence of antibiotic prescription in Nigerian hospitals is high with only about 50% of prescriptions based on clear therapeutic indications. We provide evidence that the country needs to institute a cohesive antimicrobial stewardship intervention program.