Department of Biomedical Engineering

Permanent URI for this community

https://ir.unilag.edu.ng/handle/123456789/3473

Browse

Browsing Department of Biomedical Engineering by Author "Akanmu, O. N."

Now showing 1 - 5 of 5
  • Item
    Open Access
    A Dual Slot Antenna with a Floating Metallic Sleeve for Microwave Ablation of Liver Tumor
    (Journal of Basic Medical Sciences, 2015-12-01) Nwoye, E. O.; Ibitoye, A. Z.; Adeneye, S. O.; Aweda, M. A.; Oremosun, A. A.; AnnunobI, C. C.; Akanmu, O. N.
    Full texts attached
  • Item
    Open Access
    EPROM-Based Heartbeat Monitor using Optical Biomedical Engineering Technique
    (Nig. Quaterly Journal of Hospital Medicine, 2011-06-01) Nwoye, E. O.; Oronti, I. B.; Nwaneri, S. C.; Ebuehi, O. A. T.; Akanmu, O. N.; Olasore, H.A.S.
    3. Background: In Nigeria manual methods of heartbeat monitoring are commonly used which are subjected to a number of human errors and problems. Objective: This paper describes the development of a non invasive EPROM based heartbeat monitor using optical biomedical engineering technique to detect ad count the user’s heartbeat digitally as well as provide a visual indication of the result obtained. Methods: This design and construction work employed the optical biomedical engineering technique in which tiny subcutaneous blood vessels in any patch of skin preferably the fingers furnished with a good supply of blood alternately expand and contract in time with the heartbeat. The optical sensors were planted in a peg which provides firm grip of the finger tip to sense these contraction and expansion processes. Result: The results of the tests carried out on fingers of different individuals at rest showed that the thumb, middle finger and forefinger responded more accurately to the heartbeat measurements taken. The thickness of the individual’s fingers contributed greatly to the accuracy of the measurement taken Conclusion: The EPROM based heartbeat monitor is a very efficient tool for monitoring the heartbeat of patients. However, its efficiency is determined by the thickness of the individual finger.
  • Item
    Open Access
    Microwave ablation of ex vivo bovine tissues using a dual slot antenna with a floating metallic sleeve
    (International Journal of Hyperthermia, 2016-11-11) Nwoye, E. O.; Ibitoye, A. Z.; Aweda, M. A.; Oremosun, A. A.; Anunobi, C. C.; Akanmu, O. N.
    Purpose: To study the efficiency of a dual slot antenna with a floating metallic sleeve on the ablation of different ex vivo bovine tissues. Materials and methods: COMSOL Multipurpose®version 4.4 (Stockholm, Sweden), which is based on finite element method (FEM), was used to design simulate monopole and dual slot with sleeve antennas, power, specific absorption rate (SAR) temperature and necrosis distributions in the selected tissues were determined using these antennas. Monopole and dual slot with sleeve antennas wee designed simulated constructed and applied in this study based on a semi rigid coaxial cable. Ex vivo experiment were performed on liver, lung, muscle and heart of bovine obtained from a public animal slaughter house. The microwave energy was delivered using a 2.45GHz solid state microwave generator at 40 W for 3, 5 and 10 min. aspect ratio, ablation length and ablation diameter were also determined on ablated tissues and compared with simulated results. Student’s t-test was used to compare the statistically difference between the performance of the two antennas.
  • Item
    Open Access
    Microwave Ablation: Emerging Technology in Cancer Management- A review
    (Journal of Baaic Medical Sciences, 2014-12-01) Nwoye, E. O.; Ibitoye, A. Z.; Aweda, M. A.; Oremosun, A. A..; AnnunobI, c. c.; Akanmu, O. N.; Adeleye, S. O.
    Hyperthermia therapy also called thermal therapy is a type of cancer treatment in which body tissue is exposed to high temperatures. Research has shown that high temperatures can damage and kill cancer cells, usually with minimal injury to normal tissues. The electromagnetic microwave causes water molecules to vibrate and rotate; resulting in tissue heating and subsequently cell death via thermal induced protein denaturation. Microwave ablation is emerging as an attractive modality for thermal therapy of large soft tissue in short periods of time making it suitable in the treatment of liver disease, lung malignancies, renal and adrenal tumours, and bone metastases. Microwave ablation technique in comparison with other thermal therapy techniques demonstrates higher temperature profiles, faster ablation times and larger tumour ablation volumes with minimal effect of perfusion. This review describes physics of microwave ablation, microwave therapy applications in cancer management and prospects and challenges of microwave therapy in cancer management
  • Item
    Open Access
    Optimization of Dual Slot Antenna using Floating Metallic Sleeve for Microwave Ablation
    (Elsevier Journal of Medical Engineering and Physics, 2015-01-01) Nwoye, E. O.; Ibitoye, Z. A.; Aweda, M. A.; Oremosun, A. A.; AnnunobI, C. C.; Akanmu, O. N.
    Backward heating reduction is vital in power distribution optimization in microwave thermal ablation. In this study, we optimized dual slot antenna to yield reduction in backward heating pattern along the antenna shaft with the application of floating metallic sleeve. Finite element methods were used to generate the electromagnetic (EM) field and thermal distribution in liver tissue. The position of the sleeve from the tipoff the probe (z=0mm) was varied within the range 14≤z≤22mm while sleeve lengh;;t was varied within 16≤z≤48mm interval using operating frequency of 2.45GHz. the best optimized design has reflection coefficient of -20.87 dB and axial ratio of 0.41 when the sleeve position was at 17mmand sleeve length was 18mm. experimental validation shows that inclusion of floating metallic sleeve on dual slot antenna for hepatic microwave ablation averagely increased ablation diameter and aspect ratio by 17.8% and 33.9% respectively and decreased ablation length by 11.2%.Reduction in backward heating and increase in power deposition into liver tissue could be achieved by sing this antenna to provide greater efficiency and localization of specific absorption rate in delivering microwave energy for hepatic ablation