Obstetrics and Gynaecology- Scholarly Publications

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Browsing Obstetrics and Gynaecology- Scholarly Publications by Author "Adegbesan-Omilabu, M"

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    Open Access
    Preterm delivery and low maternal serum cholesterol level: Any correlation?
    (2014) Oluwole, AA; Adegbesan-Omilabu, M; Okunade, KS
    Background: The study assessed whether low maternal serum cholesterol during early pregnancy is associated with preterm delivery. Patients and Methods: It was a prospective observational cohort study involving pregnant women at gestational age of 14-20 weeks over a period of 12 months. Blood samples were obtained to measure total serum cholesterol concentrations and the sera were then analysed enzymatically by the cholesterol oxidase: p-aminophenazone (CHOD PAP) method. Results: The study showed an incidence of 5.0% for preterm delivery in the low risk study patients. Preterm birth was 4.83-times more common with low total maternal cholesterol than with midrange total cholesterol (11.8% versus 2.2%, P = 0.024). Conclusion: Low maternal serum cholesterol (hypocholesterolaemia) is associated with preterm delivery. Optimal maternal serum cholesterol during pregnancy may have merit, therefore pregnant women should be encouraged to follow a healthy, balanced diet.
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    Open Access
    Seroprevalence of hepatitis B virus infection among pregnant women at the antenatal booking clinic of a Tertiary Hospital in Lagos Nigeria
    (2015) Adegbesan-Omilabu, M; Okunade, K; Gbadegesin, A; Olowoselu, O; Oluwole, A; Omilabu, S
    Objectives: The objectives were to determine the seroprevalence of hepatitis B virus (HBV) infection and assess the major risk factors among Nigerian pregnant women. Subjects and Methods: This was a cross‑sectional descriptive study carried out among pregnant women at the antenatal clinic of a Tertiary Hospital in Lagos, Nigeria. A total number of 150 consenting pregnant women were selected for the study. A structured pretested interviewer‑administered questionnaire was used for the data collection. Sera were collected and tested for hepatitis B surface antigen (HBsAg) and hepatitis B e antigen (HBeAg). Results: Of the150 women screened during the study, 11 (7.3%) were seropositive for HBsAg. Of these 11 women, 4 (36.4%) were also positive for HBeAg. There was no statistically significant difference in the mean ages of participants who were seropositive for HBsAg and those who were negative for the virus (P = 0.888). There were statistically significant differences in the seroprevalence of HBsAg recorded among respondents with previous surgery (odd ratio [OR] ‑ 2.97; 95% confidence interval [CI] ‑ 1.08‑16.67; P = 0.046), previously affected sibling or spouse (OR ‑ 5.03; 95% CI ‑ 1.11–25.27; P = 0.001) and those with two or more lifetime sexual partners (OR ‑ 4.11; 95% CI ‑ 2.85–9.22; P = 0.024). Conclusion: The sero‑prevalence rate of HBV infection and also its infectivity is high in Lagos, Nigeria. These findings thus support the need for a nationwide policy of routine and widespread HBV screening among pregnant women.