Department of Medicine
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Browsing Department of Medicine by Author "Abubakar, S.A"
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- ItemOpen AccessCorrelation between Wayne’s Score and Laboratory Evidence of Thyrotoxicosis in Nigeria(Medknow, 2014-07) Sabir, A.A; Iwuala, S.O; Fasanmade, O.A; Abubakar, S.A; Haruna, G.Y; Ohwovoriole, A.EBackground: The diagnosis of thyrotoxicosis is based on clinical suspicion and confirmed by thyroid function test. In Nigeria, measurements of thyroid function tests are not readily available therefore the need for clinical assessment remains paramount in the diagnosis and management of thyrotoxicosis. Objective: The objective was to determine the relationship between Wayne’s score and biochemical indices of thyroid function in Nigerians. Materials and Methods: A total of 30 newly diagnosed patients with thyrotoxicosis referred to the Endocrinology Clinic were recruited for participation in this study. All patients had detailed history taken and thorough physical examinations performed. They were also assessed using the Wayne’s score. The patients also had the biochemical evaluation of their thyroid function. The relationship between the Wayne’s score values and the biochemical indices were then correlated using the Pearson’s correlation coefficient. Results: All the patients with elevated thyroid hormones had elevated Wayne’s score. The correlation coefficient between T3 and Wayne’s score was 0.79, whereas between T4 and Wayne’s score was 0.81. The average Wayne’s score was 31.6. There was negative correlation between age and Wayne’s score (r = −0.86).Conclusion: The Wayne’s score can be used as a screening tool for thyrotoxicosis in our environment.
- ItemOpen AccessRural-urban Difference in Plasma Lipid Levels and Prevalence of Dyslipidemia in Hausa-Fulani of North-Western Nigeria(2013) Sabir, A.A; Isezuo, S.A; Ohwovoriole, A.E; Fasanmade, O.A; Abubakar, S.A; Iwuala, S; Umar, M.TObjectives:To compare the serum lipidslevels, prevalence of dyslipidaemia, and adi-posity of rural versus urban dwellers in Sokoto,Nigeria.Methods:A cross-sectional study was con-ducted in both rural and urban areas ofSokoto, Nigeria. One hundred participantswere recruited using a multi-stage samplingmethod. Demographic data and anthropomet-ric measurements were obtained. Fastingblood was drawn for assessment of totalcholesterol (TC), triglyceride (TG), high-densitylipoprotein (HDL-C) and low-density lipopro-tein (LDL-C) cholesterol. The classification ofdyslipidemia was based on the NationalCholesterol Education Program-Adult Treat-ment Panel guidelines.Results:The (mean [SD]) waist circumferenceof the urban participants (83.8 [9.5] cm) wassignificantly higher than the rural participants(79.2 [11.2] cm) (P5.030). The mean BMI ofthe urban participants (23.9 [3.9] kg/m2) washigher than the rural participants (22.2 [3.7]kg/m2)(P5.09). The mean TC was significantlyhigher in urban (175.9 [49.6] mg/dL) than ruralparticipants (148.3 [24.3] mg/dL)P,.001.Mean serum LDL-C, and TG concentrationswere higher in the urban than rural partici-pants but the difference was not statisticallysignificant. Mean serum HDL-C was alsoinsignificantly higher in the rural (51.1 [7.9]mg/dL) than in urban participants (50.2 [11.7]mg/dL) (P5.64). The most frequent dyslipide-mia was abnormally low HDL-C (13%) and thiswas more common in the urban participants(16%) than in rural participants (10%).Conclusion:This study demonstrated thatcompared to the rural dwellers, the urbandweller were more likely to be obese and hadhigher frequency of adverse plasma lipidprofile. This may have implications for rural-urban patterns of lipid related cardiovasculardisease.