Department Of Chemistry

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Browsing Department Of Chemistry by Subject "3-(Aminomethyl)coumarins"

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    Open Access
    Evaluation of Baylis–Hillman Routes to 3-(Aminomethyl)coumarin Derivatives
    (Taylor & Francis Online, 2013-10-29) Olasupo, I.; Rose, N.R.; Klein, R.; Adams, L.A.; Familoni, O.B.; Kaye, P.T.
    The relative merits of two different Baylis–Hillman approaches toward the preparation of coumarin derivatives, containing peptide-like side chains, have been explored. In one approach, use of methyl acrylate as the activated alkene requires a protecting group strategy, an approach that is not necessary when using tert-butyl acrylate.