Department of Clinical Pharmacy and Biopharmacy

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Browsing Department of Clinical Pharmacy and Biopharmacy by Subject "AIDS"

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    Open Access
    Drug Therapy Problems and Adherence amongst HIV-Positive Patients Attending a Treatment Site in Middle Belt Nigeria
    (2014) Aderemi-Williams, R.I.; Akoji, E.; Ogbo, P.
    Background: With the expansion in the accessibility of antiretroviral drugs (ARVs) in the management of people living with HIV and AIDS in resource limited environment, drug therapy problems (DTPs) can be a possible challenge. Hence the need to identify DTPs and the possible causes amongst HIV-positive patients on highly active anti- retroviral Therapy (HAART). Methods: This was a 6-month prospective study using a form designed to extract the relevant data that met the study objectives. The data col- lated were analyzed using descriptive statistical methods. Results: Most (76%) of the patients affected by DTPs were females and aged more than 15 years old (73%). A total of 18 DTPs were iden- tified. The major 5 were: unavailable prescribed medicines (30; 13.95%), undesirable effects (24; 11.16%). use of non-prescribed sedatives (23; 10.70%), use of non-prescribed antimalarial drugs (21; 9.77%) and use of herbal medicines (20; 9.30%). The major causes of the identified DTPs were: unnecessary drug therapy (59; 27.44%), non-adherence (47; 21.86%). patient needed additional therapy (36; 15.74%). and adverse drug reactions (30; 13.95%). Conclusions: DTPs exists in this treatment center and the causes include non-adherence. There is need for continual pharmacist mon- itoring and intervention with other healthcare providers as part of the pharmaceutical care plan when patients come for drug refill.