Department of Clinical Pharmacy and Biopharmacy

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Browsing Department of Clinical Pharmacy and Biopharmacy by Subject "Analgesics"

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  • Item
    Open Access
    Assessment of Prescribing Pattern and Consumption of Selected Drugs at the Lagos University Teaching Hospital (LUTH)
    (University of Lagos Journal of Basic Medical Sciences, 2017) Joda, A.E.; Ekpo, E.A.
    Background: Assessing the existing prescribing practices in a health facility is important as it helps to identify specific medicine use problems to be corrected for enhanced rational use of medicines. Objectives: The study aimed to describe current treatment practices using the World Health Organizations (WHO) core and other indicators, as well as document the consumption of analgesics, antibiotics and antihypertensive drugs at the Lagos University Teaching Hospital, Lagos, Nigeria. Materials and Methods: The study was a descriptive, retrospective study of prescriptions filed in the out-patient pharmacy department from January to December 2015. Data was collected using an adapted WHO/INRUD (International Network on Rational Use of Drugs) prescribing indicator proforma and descriptive and inferential analysis were carried out as necessary using SPSS version 20.0. P-values of ≤ 0.05 were considered significant. Results: A total of 198 prescriptions and 676 drugs were assessed. The average number of drugs per prescription was 3.41, generic prescribing was 62% and proportion of prescribed drugs actually dispensed was 45%. Antihypertensives, analgesics and antibiotics made up 42%, 14% and 14% respectively of the 676 drugs prescribed. Conclusion: The prescribing pattern in the Lagos University Teaching Hospital is not in accordance with the required WHO/INRUD standard with polypharmacy, low generic prescribing and low proportion of drugs actually dispensed. An urgent need exists for interventions to improve rational drug use in the facility.
  • Item
    Open Access
    Pattern of Analgesic use and Perception of Pain Management by Health Care Workers in a Medical Facility
    (2016) Soremekun, R.O.; Ogunjuyigbe, O.K.; Onwuchuluba, E.E.
    Background and objectives: Though analgesics are the mainstay in pain management, physicians' knowledge of pain assessment and treatment modalities could affect the management. This study sought to evaluate the pattern of analgesics prescription, healthcare professionals' knowledge and perception of pain, and its management in a secondary healthcare facility. Methods: This was a descriptive retrospective review of 16,365 prescriptions of patients within the medical facility for six months to evaluate drugs used in pain management. A cross-sectional survey of 50 healthcare professionals' knowledge and perception of pain management in the facility was also carried out through the use of a questionnaire. Results: 4,323 (26.42%) prescriptions had no pain medication. 36% of prescriptions had multiple pain medications and non-opioid analgesics (85.4%) were the most commonly prescribed. Dosage forms prescribed were oral (91.38%) >Injectable (5.08%) >dermal (2.9%). 64% of health workers perceive pain as closely connected with an underlying illness but were not familiar with standard pain management guidelines. Conclusion: There is a high volume of analgesic use and non-opioids are the most commonly prescribed in this facility. Health care practitioners connect pain and some other illnesses but standard pain management guidelines were not used.