Department of Medical Microbiology and parasitology

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Browsing Department of Medical Microbiology and parasitology by Subject "Antibiotic susceptibility"

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    The prevalence and antibiotic susceptibility patterns of various klebsiella species in clinical samples and the implications for the control of hospital-acquired infections
    (1998) Ogunsola, F.T.; Oduyebo, O.O.; Kesah, C.N.; Odugbemi, T.O.
    One hundred and filly Klebsiel/a spp were isolated from clinical samples jn the Lagos University Teaching Hospital (LUTH) between July 1996 and February 1997. A total of 140 (93.3%) of these were K pneumoniae while K. oxytoca, K. ozaenae and K. ornithinolytica made up the remaining 7°/o. The biochemical cnnracteristics v.e re studied using the API 20E (BioMerieux, France). ',II isolates produced beta-lactarnase. Antibiotic susceptibility tests were done using tho E· Test. Moc.I isolates. 47 (33%) of 150 were from the paediatric wards while the medical wards had the lowest number, 10 (7%) of 150 isolates. The biochemical characteristics conformed with the AP\ standards, with over 50°/o of strains resistant to gentamicin, amoycillin-clavulanic acid (amoxyclav), piporucillm, co-trlmoxazote and cephalothin. About 97%;. of all lsolates were sensitive to Ciprofloxacin, Nalidixic acid and Amikacin. There was no correlation between biochemical character· istics of isolates and the site of isolation but most isolates from blood culture (mostly from the paediatric wards) were resistant to gentamicin. Multi-resistant strains would appear to be endemic in the Lagos University Teaching Hospital and there is need for a concerted infection control program and a sound antibiotic policy.