Pharmaceutical Chemistry- Staff Publications
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Evaluation of the Phytochemical content, Antioxidant and Antimicrobial Activity of Citrullus Lanatus (THUNB) seed method extract
(Nigerian Journal of Scientific Research, 2017-04)The objective of the present work is to evaluate the phytochemical content, in vitro antioxidant potential and antimicrobial activity of Citrullus lanatus seed methanol extract. The methanol seed ... -
Investigation of Anti-inflammatory activity of fractions from the methanol extracts of the leaf of Tetrapleura tetraptera (Schumach & Thonn) Taub
(The Nigeria Journal of Pharmacy, 2018) -
Antioxidant and Hypoglycaemic activities of the Ethanol extract of Senecio Biafrae leaves.
(Chemical Society of Nigeria, 2017)Diabetes mellitus is among the most common disorder in developed and developing countries, it has been characterized by increased levels of oxidative stress and hyperglycaemia which are implicated in the development of ... -
Phytochemical screening and in-vitro evaluation of Free Radical Scavenging Activity of Pistia stratiotes extracts
(Asian Journal of Biomedical and Pharmaceutical Sciences, 2016)Medicinal plants have been identified and used throughout human history and many of the pharmaceuticals currently available to physicians have a long history of use as herbal remedies A large number of trado-medical uses ... -
Assessment level of physicochemical properties and trace metals of water samples from Lagos, Nigeria.
(International Journal of Advanced Research in Biological Sciences, 2015)Water quality assessment largely depends on the physicochemical parameters as well as organic and inorganic compounds that are dissolved or suspended in it. Current study investigates the physico-chemical parameters ... -
In-vitro Analytical techniques for PCBs & OCPs in Plasma Employing Solid-phase Disk Extraction Technique.
(Nig. J. Pure & Appl. Sci., 2018)Solid phase extraction techniques are generally simple, economical and use less solvent, making them more appropriate for use in epidemiological studies. The Current study was focused on application of C-18 solid phase ... -
HPLC Analysis and In-vitro Dissolution studies of fifteen brands of Diclofenac tablets sampled from Pharmacy stores within the Mainland area of Lagos state
(Nigerian Journal of Pharmaceutical and Applied Science Research, 2017)The present study aimed at analysis and in vitro dissolution studies of Diclofenac tablets sampled from Pharmacy stores within the Mainland area of Lagos state, Nigeria. Qualitative and quantitative parameters ... -
Phytochemical screening, antioxidant, antiulcer and toxicity studies on Desmodium adscendens (Sw) DC Fabaceae leaf and stem
(Tropical Journal of Pharmaceutical Research, 2018)Purpose: To assess the phytochemical profile, toxicity, as well as the antioxidant, and antiulcer activities of the methanol extracts of Desmodium adscendens stem and leaf. Methods: Maceration procedure ... -
INVESTIGATION OF DITHIZONE MODIFIED C-18 SPE SORBENTS FOR PRE-CONCENTRATION OF Zn AND Cu IN WATER SAMPLES
(FUTA Journal of Research in Sciences, 2017)A simple and sensitive solid phase extraction of Zn2+ and Cu2+ in water samples employing Dithizone modified octadecyl (C-18) SPE sorbents was investigated. The effect of phenanthroline and EDTA chelation of metals on ... -
HPLC quantification of Ascorbic Acid, Thiamine and Nicotinamide in some local edible fruits
(West African Journal of Pharmacy, 2018)Background: Health and nutritional problem continues to be of increasing concern worldwide. Fruits are good source of vitamins and mineral, it plays a vital role in our health and also helps ... -
A comparison of antioxidant and Fourier Transform Infra Red Spectroscopy (FTIR) analysis on extracts of syzygium guineeses (Myrtaceae)
(Journal of Basic and social Pharmacy Research, 2019-11)Background: Syzygium guineenses, (the most common and abundant specie in Nigeria) is a medicinal plant used by traditional practitioners in northern Nigeria for a variety of healing purposes. Objective: The main objective ... -
Green synthesis of Ag, Zn and Cu nanoparticlesfrom aqueous extract of Spondias mombin leaves and evaluation of their antibacterial activity
(2020-04)Background: Nanotechnology offers an advantage as a green route for synthesis of metal nanoparticles (NPs) with plant extracts as capping agent. Spondias mombin is a fruit-bearing tree and its ... -
Electrospun Nanofibers Sorbents for Pre-Concentration of 1,1-dichloro-2,2 bis-(4-chlorophenyl)ethylene with Subsequent Desorption by Pressurized Hot Water Extraction
(Springer-Verlag, 2011-03)Electrospun polystyrene (PS) nanofibers (130– 500 nm) incorporating a potassium salt of imidazole-1-carbodithioate were evaluated as potential sorbents for the pre-concentration of a model organochlorine pesticide; ... -
Roles of monoaminergic, antioxidant defense and neuroendocrine systems in antidepressant-like effect of Cnestis ferruginea Vahl ex DC (Connaraceae) in rats
(Elsevier, 2016-10)We have earlier reported antidepressant-like effect of Cnestis ferruginea and its bioflavonoid constituent, amentoflavone in behavioural paradigms but its effects on neurochemical and neuroendocrine systems are yet to be ... -
The Physicochemical Equivalence of Eight Brands of Amlodipine Tablets in Lagos, Nigeria
(West college of medicine, 2012-09)BACKGROUND: Amlodipine is a dihydropyridine calcium channel antagonist that is useful in the treatment of hypertension and angina pectoris. In addition to the innovator brand of this molecule, several generic brands are ... -
Quality assessment of long-lasting deltamethrin impregnated insecticide nets in Lagos, Nigeria
(IPAN, 2017-02-13)Current statistics from World Health Organization (WHO) indicated that malaria mortality in Africa has decreased by 54% across all age groups. One of the concerted efforts for this positive control is the use of long-lasting ... -
Quality assessment of amoxicillin-clavulanate potassium tablets in Lagos, Nigeria
(2012)Amoxicillin clavulanate potassium is a broad spectrum antibiotic used in the management of most bacterial infections. The innovator brand, Augmentin, is expensive, hence the need to substitute them with much cheaper generic ... -
Impact of Yoyo bitters® on the Pharmacokinetic Profile of Ciprofloxacin in Healthy Nigerian Volunteers
(2018-10-23)Ciprofloxacin and Yoyo bitters® (a liquid herbal oral preparation) are readily and widely available as prescription drug and herbal medicine, respectively in Nigeria. They are taken separately or concomitantly. The high ... -
Comparative Evaluation of Physicochemical Properties of Some Commercially Available Brands of Metformin Hcl Tablets in Lagos, Nigeria
(Japsonline, 2012-01-21)There are several generics of metformin hydrochloride tablets available within the drug delivery system globally. Availability of numerous brands of Metformin tablets in Nigerian drug market today places health practitioners ... -
Quality Assessment of Twenty Brands of Sulfadoxine-Pyrimethamine tablets marketed in Mainland area of Lagos
(Chem Soc. Nigeria, 2018-01-29)Globally, malaria remains the most important health care problem and is estimated to be responsible directly for about 3000 deaths a day worldwide. Sulphadoxine-Pyrimethamine (SP) is a combination therapy for serious malaria ...