We have earlier reported antidepressant-like effect of Cnestis ferruginea and its bioflavonoid constituent, amentoflavone in behavioural paradigms but its effects on neurochemical and neuroendocrine systems are yet to be ...

BACKGROUND: Amlodipine is a dihydropyridine calcium channel antagonist that is useful in the treatment of hypertension and angina pectoris. In addition to the innovator brand of this molecule, several generic brands are ...

Current statistics from World Health Organization (WHO) indicated that malaria mortality in Africa has decreased by 54% across all age groups. One of the concerted efforts for this positive control is the use of long-lasting ...

Amoxicillin clavulanate potassium is a broad spectrum antibiotic used in the management of most bacterial infections. The innovator brand, Augmentin, is expensive, hence the need to substitute them with much cheaper generic ...

Ciprofloxacin and Yoyo bitters® (a liquid herbal oral preparation) are readily and widely available as prescription drug and herbal medicine, respectively in Nigeria. They are taken separately or concomitantly. The high ...

There are several generics of metformin hydrochloride tablets available within the drug delivery system globally. Availability of numerous brands of Metformin tablets in Nigerian drug market today places health practitioners ...

Globally, malaria remains the most important health care problem and is estimated to be responsible directly for about 3000 deaths a day worldwide. Sulphadoxine-Pyrimethamine (SP) is a combination therapy for serious malaria ...

Quality of generic medicines should be comparable with the innovator brand and therefore interchangeable with the innovator. Affordable quality tests that assure pharmaceutical and therapeutic equivalence of generics are ...

Ethnopharmacological relevance: Trianthema portulacastrum L. (Aizoaceae) is used in traditional African Medicine for the treatment of various illnesses including dropsy, inflammation and rheumatism. Aim of the study: This ...

Thirty-two actinomycetes strains were isolated from sediment samples from 12 different sites at Lagos Lagoon and identified using standard physiological and biochemical procedures as well as 16S rDNA gene sequence analysis. ...

Objective: The aim of the study is to determine the effect of Black tea on the dissolution profile of Lisinopril tablets. Method: In vitro dissolution of Lisinopril tablets was studied in the absence of black tea as a ...

Lisinopril is an angiotensin converting enzyme inhibitor (ACEI), e!ective in lowering blood pressure in all grades of essential and renovascular hypertension. YoYo Cleanser Bitters is a liquid oral herbal medication ...

This study investigates the in vitro interactions of lisinopril with metformin which is important for the possible formulation of polypills comprising both drugs. The study was conducted using the USP apparatus II paddle ...

Background: Poultry farmers in Nigeria employ the use of various antibiotics with or without the guidance of veterinarians, to promote growth and prevent infections in poultry. Although antibiotics benefit most of its uses, ...

This study investigated the quality of atorvastatin calcium tablets marketed in Lagos, Nigeria, by evaluating and comparing their physico-chemical profiles. Evaluation of physico-chemical parameters viz: uniformity of ...

Ethnopharmacological relevance The leaf of Alchornea cordifolia (Euphorbiaceae) is used in traditional African medicine in the treatment of various neurological and psychiatric disorders including depression. Previous ...

This study used biowaiver conditions to assess bioequivalence of some generic products used in Nigeria. None of the generic samples tested met biowaiver conditions; therefore, in vivo bioequivalence studies are required ...

Aim: Herb-drug interaction is a growing concern due to the increasing consumption of herbal medicines among populations globally. Assessment of potential interaction of herbs with concomitantly administered drugs is thus ...

Oral suspensions of antibiotics are mainly available as dry powders for reconstitution. Many reconstituted antibiotic suspension is to be kept refrigerated in order to get the optimal benefit from the drug. However, many ...