N-(arylsulphonyl)tetrahydropyridinium salts: intermediates for multi-ring heterocycles. Part 1. Synthesis of hexahydropyrido[1,2-b][1,2,4]benzothiadiazine dioxides
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Date
1990
Authors
Alo, B.I.
Familoni, O.B.
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Abstract
N-(Arylsulphonyl)tetrahydropyridinium salts were obtained regiospecifically and in high yield by smooth triflate-assisted decarbonylation of the corresponding N-(arylsulphonyl)piperidine-2-carboxylic acid chlorides at room temperature. These synthons were converted into the nitroamines, which reductively cyclocondensed to give the new 9-substituted tricyclic azacycles, hexahydropyrido[1,2-b][1,2,4]benzothiadiazine 6,6-dioxides.
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Keywords
Research Subject Categories::NATURAL SCIENCES::Chemistry::Organic chemistry , N-(Arylsulphonyl)tetrahydropyridinium salts , nitroamines , cyclocondensed , tricyclic azacycles
Citation
Alo, B. I., & Familoni, O. B. (1990). N-(arylsulphonyl) tetrahydropyridinium salts: intermediates for multi-ring heterocycles. Part 1. Synthesis of hexahydropyrido [1, 2-b][1, 2, 4] benzothiadiazine dioxides. Journal of the Chemical Society, Perkin Transactions 1, (7), 1835-1838.