New lysine chromogenic substrates for trypsin
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Date
1987
Authors
Somorin, O.
Okiei, W.O.
Emokpae, T.
Ogunlesi, M.
Journal Title
Journal ISSN
Volume Title
Publisher
Elsevier Science
Abstract
Eight new direct chromogenic lysine substrates, namely N α-benzyloxycarbonyl-l-lysine 3, 5-dinitroanilide hydrochloride (l-ZLDA· Hcl), N α-benzyloxycarbonyl-l-lysine 3-nitroanilide hydrochloride (l-ZLNA· HCl), N α-benzyloxycarbonyl-l-lysine 3-nitro-5-bromoanilide hydrochloride (l-ZLNBA· HCl), N α-benzyloxycarbonyl-l-lysine 3-nitro-5-chloroanilide hydrochloride (l-ZLNCA· HCl), N α-benzyloxycarbonyl-l-lysine 3-nitro-5-fluoroanilide hyrochloride (l-ZLNFA· HCl), N α-benzyloxycarbonyl-l-lysine 3-nitro-5-iodoanilide hydrochloride (l-ZLNIA· HCl), N α-benzyloxycarbonyl-l-lysine 3-nitro-5-(methylsulphonyl) anilide hydrochloride (l-ZLNMA· HCl) and N α-benzyloxycarbonyl-l-lysine 3-nitro-5-(trifluoromethyl) anilide hydrochloride (l-ZLNTA· HCl) were synthesized by the direct condensation of N α-benzyloxycarbonyl, N ϵ-t-butyloxycarbonyl-l-lysine and 3-nitro-5X-substituted aniline,(X= F, Cl, Br, I, H, NO 2, CF 3 or SO 2 CH 3
Description
Staff publications
Keywords
Research Subject Categories::NATURAL SCIENCES::Chemistry , synthesis , lysine substrates
Citation
Somorin, O., Okiei, W., Emokpae, T., and Ogunlesi, M. (1987). New lysine chromogenic substrates for trypsin. International Journal of Biological Macromolecules, 9(1), 27-31.