Effects of Acute and sub-lethal concentrations of actellic on weight changes and haematology parameters of Clarias gariepinus

Aderolu, A.Z ; Ayoola, S. O. ; Otitoloju, A.A (2010-02-15)

Staff publications


In aquatic environment, organophosphate may cause several physiological and biochemical defects in fishes. Clarias gariepinus (mean weight 10±0.1g) was exposed to acute and sub-lethal concentrations of actellic to evaluate the toxicity of actellic organophosphate. Effect of actellic on haematological parameters and weight changes of juvenile Clarias gariepinus was also investigated. The concentrations used during the acute toxicity test were 2.00, 1.50, 1.00, 0.50 mg/l with a control of 0.00mg/l; while the concentrations of the toxicant used during the 28-days sub-lethal exposure were 0.60, 0.40, 0.20 mg/l with a control of 0.00 mg/l. The lethal concentration (LC50) value of actellic was 2.50mg/l for 96h of exposure. The results obtained from the sub-lethal exposure showed that there was a progressive decrease in weight gain of fish as the concentration of the toxicant increased. Also, haematological indices indicated that the fish became hyperglycaemic and hypoproteinaemic and the severity of this condition were directly proportional to the actellic concentration. C.gariepinus are susceptible to actellic, therefore their use in disinfection on/near fish farm or area close to aquatic environment should be discouraged.