Preoperative administration of 0.2% chlorhexidine mouthrinse reduces the risk of bacteraemia associated with intra-alveolar tooth extraction.
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Date
2014-12-01
Authors
Ugwumba, C.U.; Adeyemo, W.L.; Odeniyi, O.M.; Arotiba, G.T.; Ogunsola, F.T.
Ugwumba, C.U.
Adeyemo, W.L.
Odeniyi, O.M.
Arotiba, G.T.
Ogunsola, F.T.
Journal Title
Journal ISSN
Volume Title
Publisher
Elsevier
Abstract
The aim of the study was to investigate the effect of preoperative 0.2% chlorhexidine mouthwash on the risk of bacteraemia following routine intra-alveolar tooth extraction. The study was a randomized controlled clinical study of 101 subjects who underwent intra-alveolar dental extractions under local anaesthesia. Subjects were randomly assigned to either chlorhexidine or a control group. The chlorhexidine group had 0.2% chlorhexidine mouthwash administered for 1 min before any dental manipulation, and the control group had a mouthrinse of sterile water. Blood samples were collected at baseline, 1 min and 15 min after the dental extractions. Subculture and further identification of the isolated bacteria were performed by conventional microbiological techniques. There was a statistically significant difference in the incidence of bacteraemia between the control group (52.4%) and chlorhexidine group (27.1%) (P = 0.012). Bacteraemia was most frequently detected at 1 min after extraction (33.3%). Of the 30 subjects who had positive blood culture at 1 min, bacteraemia persisted in 8 (26.7%) of the subjects after 15 min. Bacteria isolated included Staphylococcus aureus, Actinomycetes naesulendi, Prevotella species, Streptococcus spp., and Acinetobacter iwoffii. Routine use of 0.20% chlorhexidine mouthwash before dental extraction is recommended to reduce the risk of bacteraemia following tooth extraction.
Description
Staff publications
Keywords
Bacteraemia , Chlorhexidine , Dental extraction , Research Subject Categories::ODONTOLOGY , Tooth extraction
Citation
Ugwumba, C.U., Adeyemo, W.L., Odeniyi, O.M., Arotiba, G.T. and Ogunsola, F.T. (2014). Preoperative administration of 0.2% chlorhexidine mouthrinse reduces the risk of bacteraemia associated with intra-alveolar tooth extraction. J Craniomaxillofac Surg. Vol.42(8):1783-8.