Periapical granuloma associated with extracted teeth
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Date
2011-03-21
Authors
Omoregie, F.O.
Ojo, M.A.
Saheeb, B.D.
Odukoya, O.
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Abstract
Objective: This article aims to determine the incidence of periapical granuloma from extracted teeth and correlate the
clinical diagnoses with the histopathological types of periapical granuloma.
Patients and Methods: Over a period of eight months, a prospective study designed as a routine biopsy of recoverable
periapical tissues obtained from patients who had single tooth extraction was carried out.
Results: One hundred and thirty-six patients participated in the study, with 75 (55.1%) histopathologically diagnosed
periradicular lesions. There were 23 (16.9%) cases of periapical granuloma, with a male to female ratio of 2: 1. The lesion
presented mostly between the third and fourth decades of life (n=9, 6.6%). Clinically diagnosed acute apical periodontitis
was signifi cantly associated with periapical granuloma, with predominantly foamy macrophages and lymphocytes (P<0.05).
Conclusion: Periapical granuloma appears to be a less common periapical lesion in this study compared to the previous
reports. In contrast to reports that relate to an acute fl are of the lesion with abundant neutrophilic infi ltration, this study
has shown marked foamy macrophages and lymphocytes at the acute phase, which are signifi cantly associated with
the clinical diagnosis of acute apical periodontitis. We recommend the classifi cation of periapical granuloma into early,
intermediate, and late stages of the lesion, based on the associated infl ammatory cells
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Staff publications
Keywords
Clinical diagnoses , Hispathological types , Periapical granuloma , Research Subject Categories::MEDICINE
Citation
Omoregie F O, Ojo M A, Saheeb B, Odukoya O. Periapical granuloma associated with extracted teeth. Niger J Clin Pract 2011;14:293-6