Concomitant diabetes mellitus and tuberculosis as seen in Lagos, Nigeria
Date
2007-10
Authors
Odeniyi, I.A
Fasanmade, O.A
Ogbera, A.O
Journal Title
Journal ISSN
Volume Title
Publisher
Nigeria Chapter of American Association of Clinical Endocrinologists
Abstract
Background: The frequency and enhanced severity of infection in uncontrolled diabetes were well known before the discovery of insulin. The association between tuberculosis and diabetes was noted more than a thousand years ago. The concomitant existence of these conditions has great implications of the management of either disease.
Objective: To describe the features of coexistence of both conditions (diabetes and tuberculosis) in a cohort of patients seen in a Nigerian Tertiary health care delivery centre.
Materials and methods: Medical records of patients with diabetes mellitus and tuberculosis seen at the Lagos University Teaching Hospital over a period of 3 years was entered into a standard pretested questionnaire and analysed. Data analysed included age, sex, duration of DM, anthropometric indices and drug therapy. data were expressed as percentages.
Result: The salient findings were: the majority cases were 45-54 years. males predominated and the duration of diabetes in the majority was between 1 and 10 years. Extrapulmonary TB is as rare as in the general non-diabetic population. In the chest , right upper lobe consolidation is the commonest lesion in patients with diabetes and tuberculosis while cavities are not a prominent feature.
Conclusion: patients with diabetes mellitus are prone to developing tuberculosis. the longer the duration of the diabetes, the higher the tendency to developing tuberculosis and the higher its severity. There is male preponderance of concomitant disease.
Description
Staff publications
Keywords
Diabetes mellitus , Tuberculosis , Cavities , Infection , Research Subject Categories::MEDICINE
Citation
Odeniyi IA, Fasanmade OA, Ogbera AO. (2007). Concomitant diabetes mellitus and tuberculosis as seen in Lagos, Nigeria. Nigerian Endocrine Practice, 1:4-8