Intravaginal misoprostol versus Foley catheter for cervical ripening and induction of labor
Date
2005
Authors
Afolabi, B.B.
Oyeneyin, O.L.
Ogedengbe, O.K.
Journal Title
Journal ISSN
Volume Title
Publisher
Int J Gynaecol Obstet
Abstract
Objective: To compare the efficacy and safety of 100 microg of intravaginal misoprostol with intracervical Foley catheter for cervical ripening and induction of labor.
Method: One hundred women being induced in the Lagos University Teaching Hospital, Nigeria, were randomized to receive a single 100 microg dose of misoprostol intravaginally or intracervical insertion of Foley catheter. Data analyses were by the Student's t-test and chi-square test.
Result: Misoprostol was more effective in terms of induction to delivery interval (11.84+/-5.43 versus 20.03+/-4.68 h, P<0.05), change in Bishop score, and number delivered within 24 h, in patients with a one-time successful induction. Uterine hyperactivity and rupture were more frequent in the misoprostol group.
Conclusion: A single 100 microg dose of intravaginal misoprostol is more efficacious than intracervical insertion of Foley catheter for cervical ripening and induction of labor. Further studies using lower doses are needed to determine the safest dose.
Description
Staff Publications
Keywords
Misoprostol , Intravaginal , Foley catheter , Induction of labor , Cervical ripening , Research Subject Categories::MEDICINE::Surgery::Obstetrics and women's diseases
Citation
Afolabi BB, Oyeneyin OL, Ogedengbe OK. Intravaginal misoprostol versus Foley catheter for cervical ripening and induction of labor. Int J Gynaecol Obstet. 2005 Jun;89(3):263-7. doi: 10.1016/j.ijgo.2005.02.010. Epub 2005 Apr 2. PubMed PMID: 15919393.