FTIR Solid State Interaction of Moxifloxacine With Metals
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Date
2015
Authors
Olaitan O.J.
Adepoju-Bello A.A.
Kasim L.S.
Ibitoye S.F.
Fagbohun A.B.
Journal Title
Journal ISSN
Volume Title
Publisher
African Journal of Science & Nature
Abstract
In this research, metal salts containing K , Zn , Cu and Al were used to study the interaction of metal ions
with moxifloxacin HCl using Solid state synthesis. The result obtained using Fourier Transform Infrared
-1 Spectra, showed a perturbation of the absorption band of the carbonyl groups at around 1700cm-1 in
Moxifloxacin HCl when it was triturated in solid state synthesis with Zn ,Cu and Al ,indicating an interaction with these metal ions. This interaction was however absent in K because the peak was evident at
- 1708.2 cm-1. These interactions may have an effect on therapeutic outcome of co-administration of
moxifloxacin HCl with antacids or agents containing metal ions.
Keywords: Quinolones, Moxifloxacin, Carbonyl groups, Metals ions, bidentate, polydentate.
Description
Scholarly articles
Keywords
Quinolones , Moxifloxacin , Carbonyl groups , Metal ions , Research Subject Categories::PHARMACY::Pharmaceutical chemistry
Citation
Olaitan OJ, Adepoju-Bello AA., Kasim, LS, Ibitoye SF., Fagbohun AB (2015). FTIR Solid State Interaction of Moxifloxacine With Metals. African Journal of Science & Nature Vol. 1, 12-15 (2015)