FTIR Solid State Interaction of Moxifloxacine With Metals
| dc.contributor.author | Olaitan O.J. | |
| dc.contributor.author | Adepoju-Bello A.A. | |
| dc.contributor.author | Kasim L.S. | |
| dc.contributor.author | Ibitoye S.F. | |
| dc.contributor.author | Fagbohun A.B. | |
| dc.date.accessioned | 2022-01-01T16:18:35Z | |
| dc.date.available | 2022-01-01T16:18:35Z | |
| dc.date.issued | 2015 | |
| dc.description | Scholarly articles | en_US |
| dc.description.abstract | In this research, metal salts containing K , Zn , Cu and Al were used to study the interaction of metal ions with moxifloxacin HCl using Solid state synthesis. The result obtained using Fourier Transform Infrared -1 Spectra, showed a perturbation of the absorption band of the carbonyl groups at around 1700cm-1 in Moxifloxacin HCl when it was triturated in solid state synthesis with Zn ,Cu and Al ,indicating an interaction with these metal ions. This interaction was however absent in K because the peak was evident at - 1708.2 cm-1. These interactions may have an effect on therapeutic outcome of co-administration of moxifloxacin HCl with antacids or agents containing metal ions. Keywords: Quinolones, Moxifloxacin, Carbonyl groups, Metals ions, bidentate, polydentate. | en_US |
| dc.identifier.citation | Olaitan OJ, Adepoju-Bello AA., Kasim, LS, Ibitoye SF., Fagbohun AB (2015). FTIR Solid State Interaction of Moxifloxacine With Metals. African Journal of Science & Nature Vol. 1, 12-15 (2015) | en_US |
| dc.identifier.uri | https://ir.unilag.edu.ng/handle/123456789/9865 | |
| dc.language.iso | en | en_US |
| dc.publisher | African Journal of Science & Nature | en_US |
| dc.subject | Quinolones | en_US |
| dc.subject | Moxifloxacin | en_US |
| dc.subject | Carbonyl groups | en_US |
| dc.subject | Metal ions | en_US |
| dc.subject | Research Subject Categories::PHARMACY::Pharmaceutical chemistry | en_US |
| dc.title | FTIR Solid State Interaction of Moxifloxacine With Metals | en_US |
| dc.type | Article | en_US |