Ikirydinium A: a new indole alkaloid from the seeds ofHunteria umbellata (K. Schum)
dc.contributor.author | Ajala, O.S. | |
dc.contributor.author | Piggott, A.M. | |
dc.contributor.author | Plisson, F. | |
dc.contributor.author | Khalil, Z | |
dc.contributor.author | Huang, X. | |
dc.contributor.author | Adesegun, S.A. | |
dc.contributor.author | Coker, H.A. | |
dc.contributor.author | Capon, R.J. | |
dc.date.accessioned | 2022-08-31T15:56:54Z | |
dc.date.available | 2022-08-31T15:56:54Z | |
dc.date.issued | 2011 | |
dc.description.abstract | Chemical investigations into samples ofHunteria umbellata(K. Schum) collected in Osun State, Nigeria,led to the discovery of a new indole alkaloid, ikirydinium A, featuring an unprecedented 3-alkylpyridinium-indole-2-carboxylate scaffold. Ikirydinium A was found to exhibit antimicrobial activity (IC500.6lM) againstBacillus subtilisATCC 6051. The involvement of a common intermediate in the biosynthesis of ikirydinium A and vinblastine is hypothesized | en_US |
dc.identifier.citation | Ajala, O. S., Piggott, A. M., Plisson, F., Khalil, Z., Huang, X. C., Adesegun, S. A., ... & Capon, R. J. (2011). Ikirydinium A: a new indole alkaloid from the seeds of Hunteria umbellata (K. Schum). Tetrahedron letters, 52(52), 7125-7127. | en_US |
dc.identifier.uri | https://ir.unilag.edu.ng/handle/123456789/11199 | |
dc.language.iso | en | en_US |
dc.publisher | Elsevier Ltd | en_US |
dc.subject | Indole alkaloids | en_US |
dc.subject | Hunteria umbellata | en_US |
dc.subject | Nigerian medicinal plant | en_US |
dc.subject | Natural products chemistry | en_US |
dc.title | Ikirydinium A: a new indole alkaloid from the seeds ofHunteria umbellata (K. Schum) | en_US |
dc.type | Article | en_US |