Evaluation of extracts of Triclisia suboardata Oliv and Heinsia crinita (Afz) G. Taylor for antimicrobial activity against some clinical bacterial isolates and fungi
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Date
2011-02
Authors
Abo, K.A.
Lawal, I.O.
Ogunkanmi, L.A.
Journal Title
Journal ISSN
Volume Title
Publisher
Academic Journals
Abstract
We report antimicrobial potential of extracts of roots of Triclisia subcordata and whole plant of Heinsia
crinita used as components of various herbal portions in ethnomedine in South West Nigeria to treat
acute urinogenital infections and infertility. Methanol and hexane extracts of each plant were obtained
by maceration and tested for antimicrobial activity using agar diffusion and microbroth dilution
techniques. The extracts were tested against strains of Staphylococcus aureus, Escherichia coli,
Bacillus subtilis, Pseudomonas aeruginosa and fungi including four species of Candida. The study
showed that extracts of H. crinita and T. subcordata exhibited profound antibacterial activity against the
typed and clinical isolates obtained from patients with STD and meningitis. High antifungal activity,
particularly against the Candida species was noted as Candida species are implicated in candidiasis
and vaginal thrush. Generally, the methanol extract was more effective than the hexane extracts on the
test micro-organisms. The study justifies the ethnopharmacological uses of these medicinal plants for
treatment of microbial infections.
Description
Keywords
Triclisia subcardata, Heinsia crinita, antimicrobial activity, non-gonococcal urethritis, infertility.
Citation
Abo, K.A. Lawal, I.O. Ogunkanmi, L.A. 2011. Evaluation of extracts of Triclisia suboardata Oliv and Heinsia crinita (Afz) G. Taylor for antimicrobial activity against some clinical bacterial isolates and fungi. African Journal of Pharmacy and Pharmacology. 5(2): 125-131,