Antioxidant activities of Daniellia oliveri (Rolfe) Hutch. & Dalziel and Daniellia ogea (Harms) Rolfe ex Holland (Caesalpiniaceae).

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dc.contributor.authorOlaleye, O.O.
dc.contributor.authorSofidiya, M.O.
dc.contributor.authorOgba, J.O.
dc.contributor.authorLasore, W.
dc.date.accessioned2021-04-27T11:58:04Z
dc.date.available2021-04-27T11:58:04Z
dc.date.issued2020
dc.descriptionScholarly articlesen_US
dc.description.abstractDaniellia oliveri and Daniellia ogea (Caesalpiniaceae) are medicinal plants used for their various ethnomedicinal uses. Cellular damage induced by free radicals has been implicated in several diseases. Antioxidants possess the ability to protect the body from damage caused by free radical-induced oxidative stress through the inhibition of oxidation directly or indirectly. The aim of this study is to evaluate the in-vitro antioxidant activities of the leaves and stem bark extracts of D. oliveri and D. ogea using different in vitro assays including hydroxyl radical scavenging, reducing power, ferrous ion (Fe2+) chelating and lipid peroxidation inhibitory activities. The total polyphenolic contents in the extracts were also determined using standard methods. All the extracts significantly (p < 0.05) inhibited hydroxyl radical in a concentration-dependent manner. The reducing power activity of the extracts were in the order; D. oliveri stem bark > D. ogea stem bark > D. ogea leaf > D. oliveri. Also, D. oliveri leaf had the highest lipid peroxidation inhibitory activity (IC50 = 3.71 µg/mL) compared with tocopherol and quercetin (IC50 = 4.84 and 26.58 µg/mL). The iron-chelating activity of the extracts was low compared to EDTA. Additionally, total polyphenolic content estimation revealed a considerable amount of phenolics, flavonoids and proanthocyanidins which may be responsible for the antioxidant activity exhibited by the extracts. These results provide the scientific evidence suggesting the potential antioxidant property of D. oliveri and D. ogea extracts in preventing diseases associated with oxidative stress.en_US
dc.identifier.citationOlubusola O. Olaleye, Margaret O. Sofidiya, Joy O. Ogba, Wale Lasore (2020). Antioxidant activities of Daniellia oliveri (Rolfe) Hutch. & Dalziel and Daniellia ogea (Harms) Rolfe ex Holland (Caesalpiniaceae). Tropical Journal of Natural Product Research, 4(5), 210-215en_US
dc.identifier.issn2616-0692
dc.identifier.urihttps://ir.unilag.edu.ng/handle/123456789/9375
dc.language.isoenen_US
dc.publisherNatural Product Research Group University of Beninen_US
dc.relation.ispartofseriesTropical Journal of Natural Product Research;4(5)
dc.subjectDaniellia ogeaen_US
dc.subjectDaniellia oliverien_US
dc.subjectCaesalpinioideaeen_US
dc.subjectAntioxidanten_US
dc.subjectTotal polyphenolic contenten_US
dc.subjectResearch Subject Categories::PHARMACY::Pharmacognosyen_US
dc.titleAntioxidant activities of Daniellia oliveri (Rolfe) Hutch. & Dalziel and Daniellia ogea (Harms) Rolfe ex Holland (Caesalpiniaceae).en_US
dc.typeArticleen_US
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