Prevalence and factors associated with parvovirus B19 infection among blood donors: A hospital-based study in South-West, Nigeria.

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dc.contributor.authorAwolesi, IP
dc.contributor.authorJohn-Olabode, SO
dc.contributor.authorOlorunfemi, G
dc.contributor.authorAjie, IO
dc.contributor.authorOyedeji, OA
dc.contributor.authorAkanmu, AS
dc.date.accessioned2020-11-09T08:11:42Z
dc.date.available2020-11-09T08:11:42Z
dc.date.issued2020-06-26
dc.descriptionStaff Publicationen_US
dc.description.abstractBackground: Parvovirus B19 (B19V) is a transfusion transmissible infection that can result in severe consequences in vulnerable population that includes pregnant women, immunocompromised and chronic hemolytic anemia patients. The aim of this study was to determine the prevalence and factors associated with B19V infection amongst blood donors in South–West Nigeria. Materials and Methods: We conducted a comparative cross-sectional study to determine the seroprevalence of B19V immunoglobulin M (IgM) antibody among 183 blood donors at the blood bank of a tertiary hospital. The results were analyzed with SPSS 23 software, prevalence and associated factors were determined using frequencies and logistic regression, respectively. Results: The prevalence of B19V IgM was 7.1% (95% confidence interval: 4–11) with a higher prevalence among male donors compared to females 84.6% vs. 15.4%, P = 0.54). There was a statistically significant difference in the seropositivity of B19V IgM amongst the ethnic groups with the Yoruba ethnic group having a higher proportion of B19V IgM-positive participants P = 0.04. Ethnicity, gender, and steady employment were also associated with increased odds of infection, while increasing age appeared to be protective; though none of these factors were statistically significant. Conclusion: This study has shown that there is still high exposure to transfusion transmissible B19V infection.en_US
dc.identifier.citationAwolesi IP, John-Olabode SO, Olorunfemi G, Ajie IO, Oyedeji OA, Akanmu AS. Prevalence and factors associated with parvovirus B19 infection among blood donors: A hospital-based study in South-West, Nigeria. Niger J Med 2020;29:203-7.en_US
dc.identifier.otherDOI: 10.4103/NJM.NJM_6_20
dc.identifier.urihttps://ir.unilag.edu.ng/handle/123456789/8882
dc.language.isoenen_US
dc.publisherNigerian Journal of Medicineen_US
dc.subjectBlood donorsen_US
dc.subjectParvovirusen_US
dc.subjectImmunoglobulin M antibodyen_US
dc.subjectsickle cell anaemiaen_US
dc.subjectResearch Subject Categories::MEDICINEen_US
dc.titlePrevalence and factors associated with parvovirus B19 infection among blood donors: A hospital-based study in South-West, Nigeria.en_US
dc.typeArticleen_US
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