Haematological effects of ethanolic fruit extract of Tetrapleura tetraptera in male dutch white rabbits

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dc.contributor.authorOdesanmi, S.O
dc.contributor.authorLawal, R.A
dc.contributor.authorOjokuku, S.A
dc.date.accessioned2019-09-16T11:37:06Z
dc.date.available2019-09-16T11:37:06Z
dc.date.issued2010
dc.description.abstractTetrapleura tetraptera fruit is widely used in Western Nigeria amongst men as a birth control medicine. It has been reported that feeding of extracts to animals produced some toxic effects and pathological lesions in some organs. This study was designed to investigate the haematological effects of 10 days oral administration of the ethanolic extract of Tetrapleura tetraptera (TTE) fruits in mature male rabbits. Twenty healthy acclimatized male rabbits (1.4-1.6 kg b.wt. were randomly assigned to 4 groups. Animals in groups 2, 3 and 4 were administered 50, 100 and 150 mg kg-1 b.wt. of TTE. Animals in group 1 served as the control and received only water and no extract. All animals were fasted for 18 h after withdrawal of treatment and sacrificed after anaesthesia. Venous blood sample from groups were analyzed for haematological parameters. The TTE caused significant (p<0.05) reduction in RBC and WBC.en_US
dc.identifier.citationSO Odesanmi, RA Lawal, SA Ojokuku Research Journal of Medicinal Plant 4 (4), 213-217en_US
dc.identifier.issn1819-3455
dc.identifier.urihttps://ir.unilag.edu.ng/handle/123456789/5542
dc.language.isoenen_US
dc.publisherAcademic Journalsen_US
dc.subjectResearch Subject Categories::NATURAL SCIENCES::Chemistry::Biochemistryen_US
dc.subjectTetrapleura tetrapteraen_US
dc.subjectHaematologyen_US
dc.subjectRabbitsen_US
dc.subjectPhytochemicalen_US
dc.subjectToxicityen_US
dc.subjectNigeriaen_US
dc.titleHaematological effects of ethanolic fruit extract of Tetrapleura tetraptera in male dutch white rabbitsen_US
dc.typeArticleen_US
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