Effects of molecular coatings on the compression and tableting of some pharmaceutical powders

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dc.contributor.authorPilpel, N
dc.contributor.authorIgwilo, C.I
dc.contributor.authorMalamataris, S
dc.date.accessioned2022-09-12T13:11:12Z
dc.date.available2022-09-12T13:11:12Z
dc.date.issued1991
dc.descriptionScholarly articleen_US
dc.description.abstractCoating the particles of various pharmaceutical powders with up to 10 molecular layers of paraffins, fatty acids, surfactants, silicones and polymers noticeably alters their mechanical behaviour when they are compressed into beds or formed into tablets. At low packing fractions of 0.41 the tensile strengths of the beds tend to increase, then decrease and then increase again with increasing coating concentration. At higher packing fractions of 0.82 the tensile strengths of tablets generally decrease with coating concentration and there is an inverse relationship between their tensile strength and the ratio of the elasticity to the compression of the coated powders.en_US
dc.identifier.citationPilpel, N., Igwilo, C.I. and Malamataris, S. (1991). Effects of molecular coatings on the compression and tableting of some pharmaceutical powders. International Journal of Pharmaceutics, 68, 157-166en_US
dc.identifier.urihttps://ir.unilag.edu.ng/handle/123456789/11450
dc.language.isoenen_US
dc.publisherlnternational Journal of Pharmaceuticsen_US
dc.subjectPowderen_US
dc.subjectMolecular coatingen_US
dc.subjectCompressionen_US
dc.subjectTabletingen_US
dc.subjectTensile strengthen_US
dc.subjectPlasto-elastic propertiesen_US
dc.subjectResearch Subject Categories::PHARMACYen_US
dc.titleEffects of molecular coatings on the compression and tableting of some pharmaceutical powdersen_US
dc.typeArticleen_US
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