Ikirydinium A: a new indole alkaloid from the seeds of Hunteria umbellata (K. Schum)
| dc.contributor.author | Ajala, O.S. | |
| dc.contributor.author | Piggot, A.M. | |
| dc.contributor.author | Plisson, F. | |
| dc.contributor.author | Khalil, Z. | |
| dc.contributor.author | Huang, X. | |
| dc.contributor.author | Adesegun, S.A. | |
| dc.contributor.author | Coker, H.A.B. | |
| dc.contributor.author | Capon, R.J. | |
| dc.date.accessioned | 2022-01-20T00:59:15Z | |
| dc.date.available | 2022-01-20T00:59:15Z | |
| dc.date.issued | 2011 | |
| dc.description.abstract | Chemical investigations into samples of Hunteria umbellata (K. Schum) collected in Osun State, Nigeria, led to the discovery of a new indole alkaloid, ikirydinium A, featuring an unprecedented 3-alkylpyridini um-indole-2-carboxylate scaffold. Ikirydinium A was found to exhibit antimicrobial activity (IC50 0.6 lM) against Bacillus subtilis ATCC 6051. The involvement of a common intermediate in the biosynthesis of iki rydinium A and vinblastine is hypothesized | en_US |
| dc.description.sponsorship | The University of Queensland and the Australian Research Council (LP0989954). | en_US |
| dc.identifier.citation | APA | en_US |
| dc.identifier.uri | https://ir.unilag.edu.ng/handle/123456789/10594 | |
| dc.language.iso | en | en_US |
| dc.publisher | Tetrahedron Letters | en_US |
| dc.subject | Indole alkaloids, Hunteria umbellata, Nigerian medicinal plant, Natural products chemistry. | en_US |
| dc.title | Ikirydinium A: a new indole alkaloid from the seeds of Hunteria umbellata (K. Schum) | en_US |
| dc.type | Article | en_US |