Characterization of Lipid Panel in Hiv-1 Infected Patients: A Study of Baseline and 52 Weeks Haart Patients

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dc.contributor.authorEbuehi, O.A.T.
dc.contributor.authorIdoko, KM
dc.contributor.authorAni, A
dc.date.accessioned2024-01-08T13:21:38Z
dc.date.available2024-01-08T13:21:38Z
dc.date.issued2013
dc.descriptionSchorlarly Article
dc.description.abstractThe study is to characterize lipid panels with an emphasis on HDL-C (high density lipoprotein cholesterol) sub-fractions among HIV infected subjects in Lagos, Nigeria, in order to ascertain the pattern of alterations of these parameters in patients on HAART (highly active antiretroviral therapy) for 52 weeks. Serum concentrations of HDL-C and the HDL sub-fractions, HDL-C 2 and HDL-C 3, were measured in 20 HIV positive, HAART naïve and 20 HIV positive, first-line HAART experienced subjects and compared with those of HIV negative control group matched for sex and age. Serum total cholesterol (T-Chol) and low-density lipoprotein (LDL-C) levels were increased in HAART naïve patients and decreased in HAART experienced patients as compared to controls. Triglycerides and fasting blood sugar levels were significantly elevated in HAART naïve group in comparison with the other groups. Total HDL-C and HDL-C 3 concentrations were significantly lower in HAART naïve patients than in other groups while HDL-C 2 and HDL-C 2 / HDL-C 3 ratio in contrast, were not significantly different among all the groups. It is suggested that quantitation of HDL-C sub-fractions is not a valuable risk indicator for heart disease in HIV patients HAART naïve or experienced.
dc.identifier.citationEbuehi, O.A.T., Idoko, KM, and Ani, A (2013). Characterization of Lipid Panel in HIV-1 Infected Patients: A Study of Baseline and 52 Weeks HAART Patients. American Journal of Medicine and Medical Sciences 3 (3): 44-50
dc.identifier.other10.5923
dc.identifier.urihttps://ir.unilag.edu.ng/handle/123456789/12675
dc.language.isoen
dc.publisherAmerican Journal of Medicine and Medical Sciences
dc.relation.ispartofseriesAmerican Journal of Medicine and Medical Sciences; 3(3)
dc.titleCharacterization of Lipid Panel in Hiv-1 Infected Patients: A Study of Baseline and 52 Weeks Haart Patients
dc.typeArticle
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