Colorectal carcinoma in Lagos and Sagamu, Southwest Nigeria: A histopathological review
dc.contributor.author | Abdulkareem, FB | |
dc.contributor.author | Abudu, EK | |
dc.contributor.author | Awolola, NA | |
dc.contributor.author | Elesha, SO | |
dc.contributor.author | Rotimi, O | |
dc.contributor.author | Akinde, OR | |
dc.contributor.author | Atoyebi, OA | |
dc.contributor.author | Adesanya, AA | |
dc.contributor.author | Daramola, AO | |
dc.contributor.author | Banjo, AAF | |
dc.contributor.author | Anunobi, CC | |
dc.date.accessioned | 2020-02-19T13:30:02Z | |
dc.date.available | 2020-02-19T13:30:02Z | |
dc.date.issued | 2008 | |
dc.description.abstract | AIM: To study the frequency, gender and age distribution as well as pathological characteristics of colorectal carcinoma (CRC) in Lagos and Sagamu in SW Nigeria. METHODS: This is a retrospective pathological review of histologically diagnosed CRC from 5 laboratories in Lagos & Sagamu. The clinical data, such as age, sex and clinical summary were extracted from demographic information. Cases of anal cancer were excluded from this study. RESULTS: There were 420 cases (237 males and 183 females) of CRC. It peaked in the 60-69 year age group (mean: 50.7; SD: 16.2), M:F ratio 1.3:1 and 23% occurred below 40 years. The majority was well to moderately differentiated adenocarcinoma 321 (76.4%), mucinous carcinoma 45 (10.7%) and signet ring carcinoma 5 (1.2%), and more common in patients under 40 years compared to well differentiated tumors. The recto-sigmoid colon was the most common site (58.6%). About 51% and 34% of cases presented at TNM stages Ⅱ and Ⅲ, respectively. CONCLUSION: CRC is the commonest malignant gastrointestinal (GIT) tumor most commonly located in the recto-sigmoid region. The age and sex prevalence and histopathological features concur with reports from other parts of the world. | en_US |
dc.description.sponsorship | Supported by University of Lagos Central Research Grant No. 2007/08 | en_US |
dc.identifier.citation | World J Gastroenterol 2008 November 14; 14(42): 6531-6535 | en_US |
dc.identifier.uri | https://ir.unilag.edu.ng/handle/123456789/7712 | |
dc.publisher | World Journal of Gastroenterology | en_US |
dc.subject | Colorectal carcinoma; Adenocarcinoma; Pathological staging; Histopathological characteristics | en_US |
dc.title | Colorectal carcinoma in Lagos and Sagamu, Southwest Nigeria: A histopathological review | en_US |
dc.type | Article | en_US |
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