Colorectal carcinoma in Lagos and Sagamu, Southwest Nigeria: A histopathological review

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dc.contributor.authorAbdulkareem, FB
dc.contributor.authorAbudu, EK
dc.contributor.authorAwolola, NA
dc.contributor.authorElesha, SO
dc.contributor.authorRotimi, O
dc.contributor.authorAkinde, OR
dc.contributor.authorAtoyebi, OA
dc.contributor.authorAdesanya, AA
dc.contributor.authorDaramola, AO
dc.contributor.authorBanjo, AAF
dc.contributor.authorAnunobi, CC
dc.date.accessioned2020-02-19T13:30:02Z
dc.date.available2020-02-19T13:30:02Z
dc.date.issued2008
dc.description.abstractAIM: To study the frequency, gender and age distribution as well as pathological characteristics of colorectal carcinoma (CRC) in Lagos and Sagamu in SW Nigeria. METHODS: This is a retrospective pathological review of histologically diagnosed CRC from 5 laboratories in Lagos & Sagamu. The clinical data, such as age, sex and clinical summary were extracted from demographic information. Cases of anal cancer were excluded from this study. RESULTS: There were 420 cases (237 males and 183 females) of CRC. It peaked in the 60-69 year age group (mean: 50.7; SD: 16.2), M:F ratio 1.3:1 and 23% occurred below 40 years. The majority was well to moderately differentiated adenocarcinoma 321 (76.4%), mucinous carcinoma 45 (10.7%) and signet ring carcinoma 5 (1.2%), and more common in patients under 40 years compared to well differentiated tumors. The recto-sigmoid colon was the most common site (58.6%). About 51% and 34% of cases presented at TNM stages Ⅱ and Ⅲ, respectively. CONCLUSION: CRC is the commonest malignant gastrointestinal (GIT) tumor most commonly located in the recto-sigmoid region. The age and sex prevalence and histopathological features concur with reports from other parts of the world.en_US
dc.description.sponsorshipSupported by University of Lagos Central Research Grant No. 2007/08en_US
dc.identifier.citationWorld J Gastroenterol 2008 November 14; 14(42): 6531-6535en_US
dc.identifier.urihttps://ir.unilag.edu.ng/handle/123456789/7712
dc.publisherWorld Journal of Gastroenterologyen_US
dc.subjectColorectal carcinoma; Adenocarcinoma; Pathological staging; Histopathological characteristicsen_US
dc.titleColorectal carcinoma in Lagos and Sagamu, Southwest Nigeria: A histopathological reviewen_US
dc.typeArticleen_US
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