Microwave-Assisted Solvent-Free Arylation of Amino acids with Halogenobenzenes
dc.contributor.author | Sowole, M.A. | |
dc.contributor.author | Adebisi, A.B. | |
dc.contributor.author | Olasupo, I.A. | |
dc.contributor.author | Izunobi, J.U. | |
dc.contributor.author | Familoni, O.B. | |
dc.date.accessioned | 2019-08-23T14:53:08Z | |
dc.date.available | 2019-08-23T14:53:08Z | |
dc.date.issued | 2018-06-21 | |
dc.description.abstract | The solventless microwave-assisted arylation and heteroarylation of different aliphatic and cyclic amino acids 2a–e were carried out on activated, substituted o-nitrohalogenobenzenes 1a–h and 2-chloro-3-nitropyridine 1i, in the presence of potassium carbonate and potassium fluoride for 0.5 h at 70 W, to give substituted N-(o-nitrophenyl)amino-2-carboxylic acid 3–16 and N-(m-nitropyridyl)amino-2-carboxylic acid 17–18 adducts in yields ranging from 5–98% . | en_US |
dc.identifier.uri | https://ir.unilag.edu.ng/handle/123456789/4646 | |
dc.language.iso | en | en_US |
dc.publisher | Chemical Society of Nigeria | en_US |
dc.subject | amino acids, arylation, halogenobenzenes, microwave synthesis | en_US |
dc.title | Microwave-Assisted Solvent-Free Arylation of Amino acids with Halogenobenzenes | en_US |
dc.type | Article | en_US |