Medication Adherence Among Nigerians with Schizophrenia: Correlation Between Clinico-Demographic Factors and Quality of Life

Simple item page
dc.contributor.authorOgunnubi, O.P.
dc.contributor.authorOlagunju, A.T.
dc.contributor.authorAina, O.F.
dc.contributor.authorOkubadejo, N.U.
dc.date.accessioned2019-10-31T08:18:57Z
dc.date.available2019-10-31T08:18:57Z
dc.date.issued2017-03-22
dc.descriptionStaff publicationsen_US
dc.description.abstractMedication adherence contributes significantly to symptom remission, recovery and wellbeing in mental illnesses. We evaluated how medication adherence correlates with clinico-demographic factors and quality of life (QoL) in a sample of Nigerians with schizophrenia. This descriptive cross-sectional study involved 160 randomly selected participants with confirmed diagnosis of schizophrenia based on MINI International Neuropsychiatric Interview. Data on socio-demographic and clinical characteristics of participants were collected with a questionnaire. Medication adherence was assessed with Morisky Medication Adherence Questionnaire, and participants completed the World Health Organization Quality of Life Scale-BREF. The mean age of participants was 38.54 (±11.30) years, and all the participants were on antipsychotics, but only 45% were adherent to their medication. Out of all the participants, 45 (28.2%) considered their overall QoL to be good, 97 (60.6%) considered theirs to be fair, while 18 (11.2%) reported poor QoL. Medication non-adherence correlated negatively with good QoL across multiple dimensions including overall QoL (r=-0.175), health satisfaction (r=-0.161), physical (r=-0.186) and psychological domain (r=-0.175). Again, participant's age (r=-0.190) and age of onset of illness (r=-0.172) correlated negatively with medication non-adherence, and a trend towards relapse delay with medication adherence was also observed (r=-0.155). The effect size of these correlations were however small. Our findings suggest a link between medication adherence and QoL in schizophrenia, such that strategy that addresses medication non-adherence and its determinants may have potential benefits on wellbeing. Further hypotheses-driven studies are desirable.en_US
dc.identifier.citationOgunnubi OP, Olagunju AT, Aina OF, Okubadejo NU. Medication Adherence Among Nigerians with Schizophrenia: Correlation Between Clinico-Demographic Factors and Quality of Life. Ment Illn. 2017 Mar 22;9(1):6889.en_US
dc.identifier.otherdoi: 10.4081/mi.2017.6889.
dc.identifier.urihttps://ir.unilag.edu.ng/handle/123456789/6619
dc.language.isoenen_US
dc.publisherPagepress Publicationsen_US
dc.relation.ispartofseriesMent Illn;Vol.9(1)
dc.subjectAfricaen_US
dc.subjectClinico-Demographicen_US
dc.subjectMedication adherenceen_US
dc.subjectSchizophreniaen_US
dc.subjectWellbeingen_US
dc.titleMedication Adherence Among Nigerians with Schizophrenia: Correlation Between Clinico-Demographic Factors and Quality of Lifeen_US
dc.typeArticleen_US
Files
Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
Ogunnubi PO et al. Medication Adherence Schizophrenia Mental Illness 2017.pdf
Size:
115.96 KB
Format:
Adobe Portable Document Format
Description:
Main article
Download
License bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
license.txt
Size:
1.71 KB
Format:
Item-specific license agreed upon to submission
Description:
Download
Collections
Medicine- Scholarly Publications