Prevalence, profile and predictors of malnutrition in children with congenital heart defects: a case-control observational study.
dc.contributor.author | Okoromah, C.A. | |
dc.contributor.author | Ekure, E.N. | |
dc.contributor.author | Lesi, F.E. | |
dc.contributor.author | Okunowo, W.O. | |
dc.contributor.author | Tijani, B.O. | |
dc.contributor.author | Okeiyi, J.C. | |
dc.date.accessioned | 2019-11-12T14:14:17Z | |
dc.date.available | 2019-11-12T14:14:17Z | |
dc.date.issued | 2011-04 | |
dc.description | Staff publications | en_US |
dc.description.abstract | OBJECTIVE: To investigate the prevalence, profile and predictors of severe malnutrition in children with congenital heart defects (CHDs). DESIGN: Case-control, observational study. SETTING: Tertiary teaching hospital in Lagos, Nigeria (March 2006 to March 2008). PARTICIPANTS: Children aged 3-192 months with uncorrected symptomatic CHD and healthy controls, frequency matched for age and sex. MAIN OUTCOME MEASURES: Prevalence of malnutrition based on WHO/National Center for Health Statistics/Centers for Disease Control and Prevention z score ≤-2; weight for age, weight for height/length and height for age; proportions of underweight, wasting and stunting in cases and controls, and in acyanotic and cyanotic CHD; and predictors of malnutrition using multivariate logistic analysis. RESULTS: 90.4% of cases and 21.1% of controls had malnutrition (p=0.0001), and 61.2% and 2.6%, respectively, had severe malnutrition (p=0.0001). Wasting, stunting and underweight were identified in 41.1%, 28.8% and 20.5%, and 2.6%, 3.9% and 14.5% of cases and controls, respectively. Wasting was significantly higher (58.3%) in acyanotic CHD (p=0.0001), and stunting (68.0%) in cyanotic CHD (p=0.0001). Age at weaning was significantly lower in cases than controls (3.24±0.88 and 7.04±3.04 months, respectively; p=0.0001) and in acyanotic than cyanotic CHD (2.14±0.33 and 5.33±1.22 months, respectively; p=0.004). Predictors of malnutrition in CHD were anaemia, moderate to severe congestive heart failure (CHF), poor dietary intake of fat and prolonged unoperated disease. CONCLUSION: Severe malnutrition in association with anaemia and moderate to severe CHF is highly prevalent in CHD preoperatively in these children. Early weaning may be a marker of feeding difficulties in heart failure. | en_US |
dc.description.sponsorship | University of Lagos Central Research Committee grant. | en_US |
dc.identifier.citation | Okoromah CA, Ekure EN, Lesi FE, Okunowo WO, Tijani BO, Okeiyi JC. Prevalence, profile and predictors of malnutrition in children with congenital heart defects: a case-control observational study. Arch Dis Child. 2011 Apr;96(4):354-60. | en_US |
dc.identifier.other | doi: 10.1136/adc.2009.176644. | |
dc.identifier.uri | https://ir.unilag.edu.ng/handle/123456789/6839 | |
dc.language.iso | en | en_US |
dc.publisher | BMJ | en_US |
dc.subject | congenital heart defects | en_US |
dc.subject | Malnutrition | en_US |
dc.subject | Prevalence | en_US |
dc.subject | Children | en_US |
dc.subject | Nigeria | en_US |
dc.subject | Congestive heart failure | en_US |
dc.subject | Anaemia | en_US |
dc.subject | Research Subject Categories::MEDICINE | en_US |
dc.title | Prevalence, profile and predictors of malnutrition in children with congenital heart defects: a case-control observational study. | en_US |
dc.type | Article | en_US |
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