Synthesis and in-vitro antibacterial study of some Schiff base copper (II) complexes derived from 4-phenylsemicarbazone
| dc.contributor.author | Fasina, T. M. | |
| dc.contributor.author | Dueke-eze, C. U. | |
| dc.contributor.author | Ejiah, F. N. | |
| dc.contributor.author | Ebesunun, B. E. | |
| dc.contributor.author | Oluwalana, E. A. | |
| dc.date.accessioned | 2019-09-05T16:19:19Z | |
| dc.date.available | 2019-09-05T16:19:19Z | |
| dc.date.issued | 2016-09-03 | |
| dc.description.abstract | Six new Schiff base ligands derived from the condensation of 5-substituted 2-hydroxybenzaldehyde with 4-phenylsemicarbazide (HL1-HL6) and their copper (II) complexes were synthesized and characterized using melting point, 1 H NMR and Infrared (IR). IR data confirmed that the ligands coordinated to the metal ion in a bidentate manner through the azomethine nitrogen and carbonyl oxygen resulting in metal complexes with a 1: 2 metal: ligand ratio. The Schiff bases and copper complexes exhibited good in-vitro antibacterial activity against S. aureus and E. coli in ethyl acetate with zones of inhibition ranging from 9-27 mm indicating their potential as good broad spectrum antibacterial agents. | en_US |
| dc.identifier.citation | Fasina, T. M., Dueke-Eze, C. U., Elijah, F. N., Ebesunun, B. E., & Oluwalana, E. A. (2016). Synthesis and in-vitro antibacterial study of some Schiff base copper (II) complexes derived from 4-phenylsemicarbazone. NISEB Journal, 16(3), 118-124 | en_US |
| dc.identifier.uri | https://ir.unilag.edu.ng/handle/123456789/5303 | |
| dc.language.iso | en | en_US |
| dc.subject | Research Subject Categories::NATURAL SCIENCES::Chemistry::Inorganic chemistry | en_US |
| dc.subject | Copper(II) Schiff bases, 4-phenylsemicarbazide, in-vitro, antibacterial screening | en_US |
| dc.title | Synthesis and in-vitro antibacterial study of some Schiff base copper (II) complexes derived from 4-phenylsemicarbazone | en_US |
| dc.type | Article | en_US |