Associated risk factors and pulsed field gel electrophoresis of nasal isolates of staphylococcus aureus from medical students in a tertiary hospital in lagos, nigeria

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dc.contributor.authorSolayide, A.A.
dc.contributor.authorOlusegun, A.A
dc.contributor.authorBabajide, S.B.
dc.contributor.authorBartholomew, I.C.B.
dc.contributor.authorStella, I.S.
dc.contributor.authorKehinde, O.A.
dc.contributor.authorDeborah, U.E.
dc.contributor.authorFolasade, T.O.
dc.contributor.authorAkitoye, O.C.
dc.date.accessioned2019-11-29T15:01:14Z
dc.date.available2019-11-29T15:01:14Z
dc.date.issued2007
dc.descriptionStaff publicationsen_US
dc.description.abstractStaphylococcus aureus infections are growing problems worldwide with important implications in hospitals. The organism is normally present in the nasal vestibule of about 35% of apparently healthy individuals and its carriage varies between different ethnic and age groups. Staphylococcal nasal carriage among health workers is particularly important to establish new clones and track origin of infections during outbreak situations. To determine the carriage rate and compare the pulsed field gel patterns of the strains, nasal swabs were collected from 185 medical students in a teaching hospital in Lagos, Nigeria. Isolates of S. aureus were tested for heamolysin production, methicillin sensitivity and Pulsed Field Gel Electrophoresis (PFGE) was performed. The results showed S.aureus nasal carrier rate of 14% with significant rate among males compared to females. All the isolates produced heamolysin. Antibiotic susceptibility pattern revealed that majority of the isolates was susceptible. Five strains (19%) harboured resistant determinants to penicillin and tetracycline. None of the strains was resistant to methicillin. 44% of the isolates typed by PFGE had type B, the most predominant pulsotype. PFGE A clone exhibited a single resistance phenotype suggesting a strong clonal relationship that could punctual an outbreak in the hospital. The results speculate that nasal carriage among medical personnel could be a function of various risk factors. Personal hygiene and behaviour may however be the means to reducing colonization and spread of S.aureus in our hospitals.en_US
dc.identifier.citationSolayide, A.A., Olusegun A. A., Babajide S.B., Bartholomew I. C., Stella I.S., Kehinde O.A., Deborah U.E, Folashade T. O. and Akitoye O. C.(2007). Associated Risk Factors and Pulsed Field Gel Electrophoresis of Nasal Isolates of Staphylococcus aureus from Medical Students in a Tertiary Hospital in Lagos, Nigeria. The Brazilian journal of Infectious Diseases, 11:63-69.en_US
dc.identifier.issn1678-4391
dc.identifier.urihttps://www.google.com/search?q=Associated+risk+factors+and+pulsed+field+gel+electrophoresis+of+nasal+isolates+of+Staphylococcus+aureus+from+medical+students+in+a+tertiary+hospital+in+Lagos%2C+Nigeria&oq=Associated+risk+factors+and+pulsed+field+gel+electrophoresis+of+nasal+isolates+of+Staphylococcus+aureus+from+medical+students+in+a+tertiary+hospital+in+Lagos%2C+Nigeria&aqs=chrome..69i57.1540j0j7&sourceid=chrome&ie=UTF-8
dc.identifier.urihttps://ir.unilag.edu.ng/handle/123456789/7020
dc.language.isoenen_US
dc.relation.ispartofseriesThe Brazilian journal of Infectious Diseases;Vol.11
dc.subjectPfgeen_US
dc.subjectNasal isolatesen_US
dc.subjectCarriage rateen_US
dc.subjectStaphylococcus aureusen_US
dc.subjectResearch Subject Categories::MEDICINEen_US
dc.titleAssociated risk factors and pulsed field gel electrophoresis of nasal isolates of staphylococcus aureus from medical students in a tertiary hospital in lagos, nigeriaen_US
dc.typeArticleen_US
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