Predonation Iron and Hematological Status of Whole Blood Donors in Lagos, Nigeria: Impact on Blood Supply
| dc.contributor.author | Oyedeji, OA | |
| dc.date.accessioned | 2020-01-20T12:05:33Z | |
| dc.date.available | 2020-01-20T12:05:33Z | |
| dc.date.issued | 2020-01-10 | |
| dc.description.abstract | Context: Regular blood donations can engender iron depletion and its complications; reducing the prevalence of iron depletion among blood donors is a key strategy for optimizing donors’ health. However, the factors impacting on iron deficiency among blood donors are not yet well characterized in our environment. Aim: The aim of this study is to determine predonation iron status and hematological profile among blood donors. Settings and Design: We conducted a comparative cross-sectional study of eligible blood donors at Lagos University Teaching Hospital. Consenting participants were consecutively recruited. Materials and Methods: Sociodemographic data were collected using an interviewer-administered questionnaire. Blood samples for estimation of ferritin, serum iron, total iron-binding capacity, and complete blood count were collected. Statistical Analysis Used: Statistical analysis was conducted using Stata version 14 software. Results: About three-fourths of the participants (n = 234, 74.8%) were first‑time donors and one‑fourth (n = 79, 25.2%) were frequent donors. Overall, 16 (5.1%) of the blood donors had depleted iron stores. There was a significant difference in the prevalence of iron depletion between first‑time and regular donors (P < 0.01). Multivariable analysis showed that the odds of iron deficiency decreased by 58% for every g/dl increase in hemoglobin levels (odds ratio = 0.42, 95% confidence interval: 0.24–0.73, P = 0.002). Smokers had about 14‑fold odds of having iron deficiency as compared to nonsmokers. Conclusion: Although current donation strategies to mitigate donation‑related iron loss have resulted in a significant decline in the prevalence of iron deficiency in frequent blood donors, we are still a long way from keeping our iron‑replete blood donors. | en_US |
| dc.identifier.citation | Oyedeji OA, Ajie OI, John-Olabode SO, Olorunfemi G. Predonation iron and hematological status of whole blood donors in Lagos, Nigeria: Impact on blood supply. Niger J Gen Pract 2020;18:22‑6. | en_US |
| dc.identifier.other | DOI: 10.4103/NJGP.NJGP_8_19 | |
| dc.identifier.uri | https://ir.unilag.edu.ng/handle/123456789/7466 | |
| dc.language.iso | en | en_US |
| dc.publisher | The Nigerian joural of general practice | en_US |
| dc.subject | Ferritin | en_US |
| dc.subject | iron depletion | en_US |
| dc.subject | predonation | en_US |
| dc.subject | hemoglobin | en_US |
| dc.title | Predonation Iron and Hematological Status of Whole Blood Donors in Lagos, Nigeria: Impact on Blood Supply | en_US |
| dc.type | Article | en_US |