Toxicological Evaluation and Usefulness of Lipid Peroxidation as Biomarker of Exposure to Crude Oil and Petroleum Products Tested against African Catfish, Clarias gariepinus and Hermit Crab, Clibanarius africanus

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dc.contributor.authorKing, Michael A.
dc.contributor.authorSogbanmu, Temitope O.
dc.contributor.authorOsibona, Adesola O.
dc.contributor.authorDoherty, Victoria F.
dc.contributor.authorOtitoloju, Adebayo A.
dc.date.accessioned2019-02-02T14:31:12Z
dc.date.available2019-02-02T14:31:12Z
dc.date.issued2012-03
dc.description.abstractThe toxicological evaluations of crude oil, petrol, kerosene and diesel were carried out against the African Catfish (Clarias gariepinus) fingerlings and Hermit crab (Clibanarius africanus). On the basis of 96hr LC 50 value, petrol (LC 50 = 2.449 mL/L) was found to be the most toxic followed by diesel (LC 50 = 7.839 mL/L), kerosene (LC 50 = 8.095 mL/L), and crude oil (LC 50 = 9.355 mL/L) to Clarias gariepinus. For Clibanarius africanus also, petrol (LC 50 = 4.569mL/L) was the most toxic followed by kerosene (LC 50 = 8.705 mL/L), diesel (LC 50 = 13.852 mL/L) and (LC 50 = 35.955 mL/L). On the basis of the computed susceptibility factor, hermit crab was found to be 2x, 2x, 6.1x and slightly more tolerant than catfish when exposed to petrol, diesel, crude oil and kerosene respectively. The results of the lipid peroxidation assay against juveniles of C. gariepinus showed that the level of malondialdehyde (MDA) in the liver of fish exposed to sublethal concentrations of all the test chemicals increased significantly when compared to control animals. The observed increase in MDA levels in the liver tissues of test animals exposed to crude oil and refined petroleum products was recommended as a good biomarker for early detection of oil related pollution during biomonitoring programmes.en_US
dc.identifier.citationKing, M. A., Sogbanmu, T. O., Osibona, A. O., Doherty, V. F. and Otitoloju, A. A. (2012). Toxicological evaluations and usefulness of lipid peroxidation as biomarker of exposure to crude oil and petroleum products tested against Clarias gariepinus and Clibanarius africanus.en_US
dc.identifier.issn0972-6268
dc.identifier.urihttps://ir.unilag.edu.ng/handle/123456789/3557
dc.language.isoenen_US
dc.publisherNature Environment and Pollution Technologyen_US
dc.subjectToxicological evaluationen_US
dc.subjectPetroleum productsen_US
dc.subjectLipid peroxidationen_US
dc.subjectBiomarkeren_US
dc.subjectHermit craben_US
dc.subjectAfrican catfishen_US
dc.subjectResearch Subject Categories::NATURAL SCIENCESen_US
dc.titleToxicological Evaluation and Usefulness of Lipid Peroxidation as Biomarker of Exposure to Crude Oil and Petroleum Products Tested against African Catfish, Clarias gariepinus and Hermit Crab, Clibanarius africanusen_US
dc.typeArticleen_US
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