Interaction between Ciprofloxacin and some metal ions.

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dc.contributor.authorAdepoju-Bello A.A.
dc.contributor.authorCoker H.A.B.
dc.contributor.authorAbioye A.O.
dc.contributor.authorAyoola G.A.
dc.date.accessioned2022-01-08T14:58:33Z
dc.date.available2022-01-08T14:58:33Z
dc.date.issued2009
dc.descriptionScholarly articlesen_US
dc.description.abstractPurpose: Solid state synthesis of a compound is not so common. Concomitant administration of quinolones with metal ion containing drug preparations, food supplements and fruit juices have been reported to cause a reduction in the activity of quinolones. Objective: This study was carried out to determine if there is an interaction between ciprofloxacin and the metal ions in the solid state. Method: Divalent, Zn2+, Cu2+ and trivalent, Al3+, were used for the study. The pure ciprofloxacin (CIP)sample, triturated fluoroquinolone and metal ion in the solid state and the metal ions were analysed using FT-IR spectrophotometer. Result: The results obtained showed a carbonyl absorption band at 1708.2 cm-1 for ciprofloxacin, which was absent on the ciprofloxacin-metal complex infrared spectrum indicating an interaction. Conclusion: There was an interaction between ciprofloxacin and the metal ions at the solid state.en_US
dc.identifier.citationAdepoju-Bello AA, Coker HAB, Abioye AO, Ayoola GA, (2009). Interaction between Ciprofloxacin and some metal ions. J. Pharm. Sci. & Pharmaceut. Prac. 9 (1): 45- 47.en_US
dc.identifier.issn11170816
dc.identifier.urihttps://ir.unilag.edu.ng/handle/123456789/10024
dc.language.isoenen_US
dc.publisherJ. Pharm. Sci. & Pharmaceut. Prac.en_US
dc.subjectResearch Subject Categories::PHARMACYen_US
dc.subjectCiprofloxacinen_US
dc.subjectSolid state interactionen_US
dc.subjectCiprofloxacin- metal complexen_US
dc.subjectMetal ionsen_US
dc.subjectResearch Subject Categories::PHARMACYen_US
dc.titleInteraction between Ciprofloxacin and some metal ions.en_US
dc.typeArticleen_US
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