Prevalence of multi-resistant strains of pseudomonas aeruginosa isolated at the lagos university teaching hospital laboratory from 1994 to 1996

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Oduyebo, O.
Ogunsola, F.T.
Odugbemi, T.
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A total of 114 strains of Pseuaomoces aeruginosa isolated from the Lagos University Teaching Hospital (LUTH) Microbiology Laboratory, between November 1994 and Dec�mber 1996, ldentitied using analytical protite index system (API 20 NE) were checked tor susceptibility and resistance against varlous antimicrobial agents on Mueller-Hinlon agar using E test method as recommended by the National Committee on Clinical Laboratory Standards (NCCLS). Ninety-two percent, 39.7%, 21.6% and 12.5% of lsolates were found lo be resistant to arnoxycillm-clavulanate, cefotaxime, piperaciltln and imipenem respectively. Ninety-six percent, 54.2°!o, 60°/o and 95.So/o al iso- ,1' tales were susceptible to ciprolloxacin, celtazidime, gentamlcin and amikacin respectively. · Twenty-seven percent of all isolates were found to be multi-resistant and there was a gradual increase in the percentage al multi-resistant strains observed trorn 1994 to 1996. A very high percentage of isolates- resistant to piperacillin were also resistant to ticarcillin, cefotaxime and gentamicin, among olher antibiotics. Forty percent of isolates were found to be resistant to gentamicin and 86°/o of these gentamiqin resistant isolates · were multi-resistant. Forty-five percent of all isolates were found to be resistant" to celtazidime and 95.5°/o of those· celtazidime resistant strains were found to be multi-resistam. The high prevalence of multl-resistant strains in this study probably emphasizes the need for antibiotic policies in LUTH.
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Pseudomonas aeruginosa multiresistant , Gonlamicin , Ceflazidime , Luth , Research Subject Categories::MEDICINE::Microbiology, immunology, infectious diseases
Oduyebo, O, Ogunsola F.T. and Odugbemi T. (1997). Prevalence of multi-resistant strains of Pseudomonas aeruginosa isolated at the Lagos University Teaching Hospital from 1994 to 1996. Nigerian Quarterly Journal of Hospital Medicine. 7 (4):373 - 376.