Nigerian Pediatric Cardiology Study Group. Congenital Heart Defects in Nigerian Children: Preliminary Data From the National Pediatric Cardiac Registry
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Date
2017-11
Authors
Ekure, E.N.
Bode-Thomas, F.
Sadoh, W.E.
Orogade, A.A.
Otaigbe, B.E.
Ujunwa, F.
Sani, U.M.
Asani, M.
Animasahun, A.B.
Ogunkunle, O.C.
Journal Title
Journal ISSN
Volume Title
Publisher
Sage Publishing
Abstract
Background: Congenital heart defects (CHDs) are common birth defects with significant impact on morbidity and mortality.
We aimed to compare regional patterns of CHDs in Nigeria using a registry-based approach. Methods: Children with
echocardiography-confirmed CHDs at 17 medical centers across the country were enrolled in a pilot National Pediatric Cardiac
Registry from January to December 2014. Results: A total of 1,296 children (52.9% male; median age 0.9 years) with CHDs were
enrolled. Patients enrolled in Northern Nigeria constituted 34.6% of the study population and were older compared to those
enrolled from Southern Nigeria (2.9 + 3.6 vs 2.4 + 3.5 years; P ¼ .02). Ventricular septal defects were significantly more
prevalent in the North (37.4%) compared with the South (18.5%; P < .0001), while severe CHDs were more prevalent in
the South (P ¼ .004). Of the 208 (16.0%) children who received corrective cardiac intervention, only 43 (20.7%) of them had the
intervention done in country. More patients in the South received intervention compared to the North (19.02% vs 10.5%;
P < .0001). Conclusion: This is the first prospective, registry-based, multicenter study of CHDs in Nigerian children. We
demonstrate important differences between the Northern and the Southern geographical regions of the country in terms of age
at diagnosis, type, and severity of lesion as well as access to cardiac surgery. The findings demonstrate the utility of a national
CHDs registry for understanding clinical epidemiology of CHDs in low- and middle-income countries and its potential to serve as
a basis for research and planning.
Description
Staff publications
Keywords
congenital heart defect , congenital heart disease , disease registry , Pediatric , Research Subject Categories::MEDICINE
Citation
Ekure EN, Bode-Thomas F, Sadoh WE, Orogade AA, Otaigbe BE, Ujunwa F, Sani UM, Asani M, Animasahun AB, Ogunkunle OO; Nigerian Pediatric Cardiology Study Group. Congenital Heart Defects in Nigerian Children: Preliminary Data From the National Pediatric Cardiac Registry. World J Pediatr Congenit Heart Surg. 2017 Nov;8(6):699-706.