The phytochemistry and gastroprotective activities of the leaves of Ficus glumosa

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dc.contributor.authorAwolola, G.V.
dc.contributor.authorSofidiya, M.O.
dc.contributor.authorBaijnath, H.
dc.contributor.authorNoren, S.S.
dc.contributor.authorKoorbanally, N.A.
dc.date.accessioned2021-04-15T14:22:26Z
dc.date.available2021-04-15T14:22:26Z
dc.date.issued2019
dc.descriptionScholarly articlesen_US
dc.description.abstractFicus glumosa is reputed for the treatment and management of various health conditions, including diarrhoea, dysentery, oedema, headache, stomach ailments and ulcers. Three phenolic acids (1–3), two coumarins (4 and 5), three flavonoid glycosides (6, 7a, 7b) and five triterpenoids (8–12) were isolated from the aerial parts of F. glumosa. Gastroprotective activity of the methanol soluble extract of the leaves was apparent at 200 mg kg−1 with significant protection in ethanol, indomethacin and pylorus-induced experimental ulcer models. The extract was shown to be non-toxic at 2 g kg−1. Quercetin-3-O-β-D-glucopyranoside (isoquercitrin) 7a, quercetin-3-O-β-D-galactopyranoside 7b and p-hydroxybenzoic acid 1 isolated from the leaf extract probably play a role in the observed gastroprotective activity. The findings in this study validate the use of F. glumosa in the treatment of ulcers in African ethnomedicine.en_US
dc.identifier.citationG.V. Awolola, M.O. Sofidiya, H. Baijnath, S.S. Noren, N.A. Koorbanally (2019). The phytochemistry and gastroprotective activities of the leaves of Ficus glumosa. South African Journal of Botany, 126, 190-195.en_US
dc.identifier.issn0378-8741
dc.identifier.urihttps://ir.unilag.edu.ng/handle/123456789/9294
dc.language.isoenen_US
dc.publisherElsevieren_US
dc.relation.ispartofseriesSouth African Journal of Botany;126
dc.subjectCytoprotectionen_US
dc.subjectFicus glumosaen_US
dc.subjectToxicityen_US
dc.subjectUlcer modelen_US
dc.subjectResearch Subject Categories::PHARMACY::Pharmacognosyen_US
dc.titleThe phytochemistry and gastroprotective activities of the leaves of Ficus glumosaen_US
dc.typeArticleen_US
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