Prevalence of fungal infections in immunosuppressed patients in lagos university teaching hospital - a preliminary report

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Oduyebo, O.O.
Dogunro, S.
Onwuezobe, I.A.
Ogunsola, F.T.
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Introduction: There is paucity of data on prevalence of fungal infections in this environment. A prevalence survey was therefore carried out to ascertain the benefit of prophylactic and therapeutic antifungal therapy in immune suppressed patients. Methodology: lmmunosuppressed patients who had systemic infections were selected based on pre-designed clinical and laboratory criteria. Specimens which included blood, sputum, urine and throat swab were aseptically collected from them and examined by microscopy and culture Result: Candida spp was cultured from seven of the 100 patients but only five were confirmed cases of Candidiasis. Four of the isolates were Candida albicans. Of the five cases of candidiasis, two were patients with Diabetes mellitus, one had AIDS, one had a malignancy and the remaining one was a patient who had septicemia and had been on antibiotic for a long time. The five cases of candidiasis were two urinary tract infections, two blood stream infections and a case of pharyngitis. No other fungus apart from Candida was cultured. Conclusion: The low prevalence of fungal infeclion obtained in this study may actually be an under estimate. Isolates were from AIDS and Diabetes mellitus patients. There is need for a future survey of the susceptible populations
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Fungal infections , Patients , Prophylactic , Systematic infections , Research Subject Categories::MEDICINE::Microbiology, immunology, infectious diseases
Oduyebo, O.O, Dogunro, S, Onwuezobe, I.A. and Ogunsola, F.T. (2003). Prevalence Of Fungal Infections in Immunosuppressed Patients in Lagos University Teaching Hospital - A Preliminary Report. Nigerian Quarterly Journal of Hospital Medicine, 13:48-51.