Evaluation of antioxidant activity of Tetracarpidium conophorum (M¨ull. Arg) Hutch & Dalziel leaves

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dc.contributor.authorAmaeze, O.U.
dc.contributor.authorAyoola, G.A.
dc.contributor.authorSofidiya, M.O.
dc.contributor.authorAdepoju-Bello, A.A.
dc.contributor.authorAdegoke, A.O.
dc.contributor.authorCoker, H.A.B.
dc.date.accessioned2021-04-19T09:51:13Z
dc.date.available2021-04-19T09:51:13Z
dc.date.issued2011
dc.descriptionScholarly articlesen_US
dc.description.abstractThis study evaluated the antioxidant activity as well as bioflavonoid content of the methanol and ethanol-water extracts of the fresh and dried leaves of Tetracarpidium conophorum. Antioxidant activity was determined by spectrophotometric methods using DPPH free radical, nitric oxide radical inhibition and ferric reducing antioxidant power assays. In addition, total phenolics, flavonoids and proanthocyanidin content were also determined. The ethanol: water extract of the dried leaves had the highest antioxidant activity with a 50% inhibition of DPPH at a concentration of 0.017 mg/mL compared to the standards, Vitamin C and Vitamin E with inhibition of 0.019 and 0.011 mg/mL, respectively. This extract also showed nitric oxide radical inhibition activity comparable to that of rutin, 54.45% and 55.03% for extract and rutin, respectively, at 0.1 mg/mL. Ferric reducing power was also comparable to that of ascorbic acid (281 and 287 μM Fe (11)/g, resp.) at a concentration of 1 mg/mL. The methanol extract of both the dried and the fresh leaves had higher phenolic, flavonoids and proanthocyanidin content than the ethanol : water extract. The study reveals that T. conophorum can be an interesting source of antioxidants with their potential use in different fields namely food, cosmetics and pharmaceuticals.en_US
dc.identifier.citationO. U. Amaeze, G. A. Ayoola, M.O. Sofidiya, A. A. Adepoju-Bello, A. O. Adegoke, H. A. B. Coker (2011). Evaluation of antioxidant activity of Tetracarpidium conophorum (M¨ull. Arg) Hutch & Dalziel leaves. Oxidative Medicine and Cellular Longevity Volume 2011, 7 pages.en_US
dc.identifier.issn1942-0994
dc.identifier.urihttps://ir.unilag.edu.ng/handle/123456789/9321
dc.language.isoenen_US
dc.publisherHindawi Publishing Corporationen_US
dc.subjectTetracarpidium conophorumen_US
dc.subjectAntioxidanten_US
dc.subjectspectrophotometric methodsen_US
dc.subjectEthanolen_US
dc.subjectResearch Subject Categories::PHARMACY::Pharmacognosyen_US
dc.titleEvaluation of antioxidant activity of Tetracarpidium conophorum (M¨ull. Arg) Hutch & Dalziel leavesen_US
dc.typeArticleen_US
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