Synthesis and biological properties of N2O2 Schiff bases derived from o-phenylenediamine and substituted salicylaldehydes

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dc.contributor.authorFasina, T.M.
dc.contributor.authorOgundele, O.O.
dc.contributor.authorAyeni, I.
dc.date.accessioned2019-09-05T16:10:04Z
dc.date.available2019-09-05T16:10:04Z
dc.date.issued2014
dc.description.abstractThree symmetrical and two unsymmetrical N2O2 Schiff bases obtained from the condensation of o-phenylenediamine with various salicylaldehydes namely salicylaldehyde, 5-nitrosalicylaldehyde and 5-bromosalicylaldehyde were synthesized and characterized based on elemental analysis, IR, 1H NMR and electronic absorption spectroscopy. The antimicrobial activity of the compounds tested against the microorganisms E. coli (ATCC 25922), E. feacalis (ATCC 29212) and S. aureus (ATCC 25923) using the agar ditch method showed a dependence on the substituent present in order H>NO2>Br. The unsymmetrical compounds exhibited higher activity compared to the symmetrical compounds.en_US
dc.identifier.citationFasina, T. M., Ogundele, O. O., & Ayeni, I. (2014). Synthesis and biological properties of N2O2 Schiff bases derived from o-phenylenediamine and substituted salicylaldehydes. J. Chem. Pharm. Res, 6, 816-819.en_US
dc.identifier.urihttps://ir.unilag.edu.ng/handle/123456789/5271
dc.language.isoenen_US
dc.publisherJournal of chemical and pharmaceutical researchen_US
dc.subjectResearch Subject Categories::NATURAL SCIENCES::Chemistry::Inorganic chemistryen_US
dc.subjecto-phenylenediamineen_US
dc.subjectsymmetricalen_US
dc.subjectSchiff baseen_US
dc.subjectantimicrobial activityen_US
dc.subjectunsymmetricaen_US
dc.titleSynthesis and biological properties of N2O2 Schiff bases derived from o-phenylenediamine and substituted salicylaldehydesen_US
dc.typeArticleen_US
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