In vitro equivalence studies of generic metformin hydrochloride tablets and propranolol hydrochloride tablets under biowaiver conditions in Lagos State, Nigeria
| dc.contributor.author | Akinleye, M.O. | |
| dc.contributor.author | Oyetunde, O.O. | |
| dc.contributor.author | Tayo, F. | |
| dc.contributor.author | Aina, B.A. | |
| dc.date.accessioned | 2019-09-17T08:03:43Z | |
| dc.date.available | 2019-09-17T08:03:43Z | |
| dc.date.issued | 2012-11 | |
| dc.description | Staff publications | en_US |
| dc.description.abstract | This study used biowaiver conditions to assess bioequivalence of some generic products used in Nigeria. None of the generic samples tested met biowaiver conditions; therefore, in vivo bioequivalence studies are required to ascertain therapeutic equivalence. To take advantage of the cost savings of using in vitro dissolution as a surrogate for bioequivalence studies, manufacturers of generic products need to consider factors that affect solubility and permeability of their products when formulating them. | en_US |
| dc.identifier.citation | Akinleye, M.O., Oyetunde, O.O., Tayo, F. and Aina, B.A. (2012). In vitro equivalence studies of generic metformin hydrochloride tablets and propranolol hydrochloride tablets under biowaiver conditions in Lagos State, Nigeria. | en_US |
| dc.identifier.uri | https://ir.unilag.edu.ng/handle/123456789/5645 | |
| dc.language.iso | en | en_US |
| dc.publisher | Dissolution Technologies | en_US |
| dc.subject | Biowaiver | en_US |
| dc.subject | in-vitro dissolution | en_US |
| dc.subject | Metformin | en_US |
| dc.subject | propranolol | en_US |
| dc.subject | Research Subject Categories::NATURAL SCIENCES::Chemistry | en_US |
| dc.title | In vitro equivalence studies of generic metformin hydrochloride tablets and propranolol hydrochloride tablets under biowaiver conditions in Lagos State, Nigeria | en_US |
| dc.type | Article | en_US |