Hematologic Abnormalities in Treatment-Naïve HIV patients

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dc.contributor.authorAkinbami, A.
dc.contributor.authorOshinaike, O.
dc.contributor.authorAdeyemo, T.
dc.contributor.authorAdediran, A.
dc.contributor.authorDosumu, O.
dc.contributor.authorDada, M.
dc.contributor.authorDurojaiye, I.
dc.contributor.authorAdebola, A.
dc.contributor.authorOsunkalu, V.
dc.date.accessioned2020-11-17T09:57:23Z
dc.date.available2020-11-17T09:57:23Z
dc.date.issued2010
dc.descriptionStaff Publicationsen_US
dc.description.abstractObjectives: Hematologic abnormalities, indicated by a deranged full blood count, are common manifestations and important prognostic tools for human immunodeficiency virus (HIV) infection and AIDS. This study aimed to determine the prevalence of cytopenia and its relationship to the degree of immunosupression in HIV treatment-naïve patients. Methods: This was a cross-sectional study of treatment-naïve HIV-infected clients who enrolled at the HIV clinic of Lagos State University Teaching Hospital (LASUTH) between December 2009 and June 2010. Participants had samples taken for full blood count and CD4 counts, which are free routine pre-requisite and pre-treatment evaluations done for all registered HIV patients at LASUTH. They were asked to fill the structured questionnaires to obtain demographic data, with assistance if necessary. Results: A total of 205 cases were reviewed: 24.2% had anemia (PCV , 30%), 26.8% had leucopenia (white blood cell ,4,000/L) and 16.1% had thrombocytopenia (platelet count ,150,000/L) at enrollment. The degree of cytopenia was directly related to the degree of immunosupression. Conclusion: About one-fifth of HIV treatment-naïve patients were cytopenic at enrollment and the degree of cytopenia was directly related to the degree of immunosupression. It is necessary to investigate various causes of cytopenia in these patients so as to administer a specific intervention.en_US
dc.identifier.citationAkinsegun, A., Oshinaike, O., Adeyemo, T., Adediran, A., Dosumu,O., Dada, M., Durojaiye, I., Adebola, A., Osunkalu, V. (2010). Hematologic Abnormalities in Treatment-Naïve HIV patients. Infectious Disease: Research and Treatment, 3:45-49.en_US
dc.identifier.otherdoi: 10.4137/IDRT.S6033
dc.identifier.urihttps://ir.unilag.edu.ng/handle/123456789/8944
dc.language.isoenen_US
dc.publisherInfectious Disease: Research and Treatmenten_US
dc.relation.ispartofseriesInfectious Disease: Research and Treatment;Vol.3
dc.subjectHIVen_US
dc.subjecthematological abnormalitiesen_US
dc.subjectNigeriaen_US
dc.subjectAIDSen_US
dc.subjectcytopeniaen_US
dc.subjectResearch Subject Categories::MEDICINEen_US
dc.titleHematologic Abnormalities in Treatment-Naïve HIV patientsen_US
dc.typeArticleen_US
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