Cytogenetic effects of two food preservatives, Sodium Metabisulphate and Sodium Benzoate on root tips of Allium cepa Linn

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dc.contributor.authorOnyemaobi, O.I.
dc.contributor.authorWilliams, G. O.
dc.contributor.authorAdekoya, K.O.
dc.date.accessioned2019-01-17T07:58:28Z
dc.date.available2019-01-17T07:58:28Z
dc.date.issued2012-06
dc.description.abstractAllium cepa assay has been used extensively to determine the cytotoxicity and genotoxicity of compounds on plants and animals. The cytogenetic effects of two commonly used food preservatives, sodium benzoate and sodium metabisulphite were evaluated using the A. cepa assay. The parameters scored for the different concentrations of the compounds tested are: root length, chromosomal aberrations and Mitotic Index. The Mitotic Index (MI) decreased with increasing concentration of both sodium benzoate and sodium metabisulphite. Cytological aberrations observed were clumping, fragmentation, pulverization, lagging, binucleate cells and reduction in chromatin materials. Clumping and fragmentation were the most frequent aberrations. The percentage of chromosomal aberrations at mitosis increased with increase in concentration of the food preservatives. The effects of sodium metabisulphite at the different concentrations in this study were very detrimental as more aberrations were recorded even after the recovery experiment. The results of this experiment show that these additives had irreversible cytotoxic effects at some levels of dosage. It supports the call for the banning of these substances as food preservatives.en_US
dc.description.sponsorshipIfe Journal of Scienceen_US
dc.identifier.citationOnyemaobi, O.I., Williams, G.O., and Adekoya, K.O. (2012). Cytogenetic effects of two food preservatives, Sodium Metabisulphate and Sodium Benzoate on root tips of Allium cepa Linn. Ife Journal of Science 14(1): 155 -165.en_US
dc.identifier.issn0794 - 4896
dc.identifier.urihttp://ir.unilag.edu.ng:8080/handle/123456789/3527
dc.language.isoenen_US
dc.publisherFaculty of Science Obafemi Awolowo University, Ile -Ife Nigeriaen_US
dc.subjectChromosome Aberrationsen_US
dc.subjectFood Preservativesen_US
dc.subjectMitotic Indexen_US
dc.subjectAllium cepa Assayen_US
dc.titleCytogenetic effects of two food preservatives, Sodium Metabisulphate and Sodium Benzoate on root tips of Allium cepa Linnen_US
dc.typeArticleen_US
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