In Vitro Transformation of Sol-gel Derived Bioactive Glass from Sand
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Date
2015-12-02
Authors
Adams, L.A.
Essien, E. R
Journal Title
Journal ISSN
Volume Title
Publisher
NWPII
Abstract
A Bioactive glass in the quaternary system SiO2–Na2O–CaO–P2O5 was prepared from sand as precursor
in place of alkoxysilanes such as tetraethyl orthosilicate (TEOS) and tetramethyl orthosilicate (TMOS).
Sodium metasilicate extracted from the sand was processed to a gel via the sol-gel technique. The gel, after
aging was dried at lower temperatures before sintering at 950 oC for 3 h to form Na2Ca2Si3O9 crystals for
enhanced mechanical property. The glass monolith was then subjected to standard in vitro bioactivity study
in simulated body fluid (SBF) over 0-21 days. Characterization of the samples before and after immersion in
SBF were performed using mechanical tester, scanning electron microscopy (SEM), energy dispersive X-ray
(EDX), X-ray diffraction and Fourier transform infrared (FTIR) to evaluate compression strength,
morphology, composition, diffraction patterns and chemical bonding respectively. The compression strength
of the glass was 1.77 Mpa. The major crystalline phase was Na2Ca2Si3O9 which, however, transformed to an
amorphous phase in SBF while forming hydroxyapatite (HA) and hydroxycarbonate apatite (HCA). The
material may be a useful candidate in the regeneration of trabecular bones
Description
Keywords
Silica source , Na2Ca2Si3O9 , Trabecular bone , Hydroxycarbonate apatite
Citation
Adams, L. A., & Essien, E. R. (2015). In Vitro Transformation of Sol-gel Derived Bioactive Glass from Sand. Am. J. Biomed. Sci, 7(4), 218-228.