In Vitro Transformation of Sol-gel Derived Bioactive Glass from Sand

dc.contributor.authorAdams, L.A.
dc.contributor.authorEssien, E. R
dc.date.accessioned2019-01-08T10:02:22Z
dc.date.available2019-01-08T10:02:22Z
dc.date.issued2015-12-02
dc.description.abstractA Bioactive glass in the quaternary system SiO2–Na2O–CaO–P2O5 was prepared from sand as precursor in place of alkoxysilanes such as tetraethyl orthosilicate (TEOS) and tetramethyl orthosilicate (TMOS). Sodium metasilicate extracted from the sand was processed to a gel via the sol-gel technique. The gel, after aging was dried at lower temperatures before sintering at 950 oC for 3 h to form Na2Ca2Si3O9 crystals for enhanced mechanical property. The glass monolith was then subjected to standard in vitro bioactivity study in simulated body fluid (SBF) over 0-21 days. Characterization of the samples before and after immersion in SBF were performed using mechanical tester, scanning electron microscopy (SEM), energy dispersive X-ray (EDX), X-ray diffraction and Fourier transform infrared (FTIR) to evaluate compression strength, morphology, composition, diffraction patterns and chemical bonding respectively. The compression strength of the glass was 1.77 Mpa. The major crystalline phase was Na2Ca2Si3O9 which, however, transformed to an amorphous phase in SBF while forming hydroxyapatite (HA) and hydroxycarbonate apatite (HCA). The material may be a useful candidate in the regeneration of trabecular bonesen_US
dc.identifier.citationAdams, L. A., & Essien, E. R. (2015). In Vitro Transformation of Sol-gel Derived Bioactive Glass from Sand. Am. J. Biomed. Sci, 7(4), 218-228.en_US
dc.identifier.issn1937-9080
dc.identifier.urihttp://ir.unilag.edu.ng:8080/handle/123456789/3495
dc.language.isoenen_US
dc.publisherNWPIIen_US
dc.subjectSilica sourceen_US
dc.subjectNa2Ca2Si3O9en_US
dc.subjectTrabecular boneen_US
dc.subjectHydroxycarbonate apatiteen_US
dc.titleIn Vitro Transformation of Sol-gel Derived Bioactive Glass from Sanden_US
dc.typeArticleen_US
Files
Original bundle
Now showing 1 - 1 of 1
Loading...
Thumbnail Image
Name:
AJBMS_2015_4_03.pdf
Size:
442.27 KB
Format:
Adobe Portable Document Format
Description:
main article
License bundle
Now showing 1 - 1 of 1
Loading...
Thumbnail Image
Name:
license.txt
Size:
1.71 KB
Format:
Item-specific license agreed upon to submission
Description: