Synthesis and Antimicrobial Activity of Schiff Bases derived from substituted Salicyladehyde with 2-aminophenol and 2-aminothiophenol
dc.contributor.author | Fasina, T.M. | |
dc.contributor.author | Ejiah, F.N. | |
dc.contributor.author | Dueke-Eze, C.U. | |
dc.contributor.author | Idika, N. | |
dc.date.accessioned | 2019-09-23T10:50:45Z | |
dc.date.available | 2019-09-23T10:50:45Z | |
dc.date.issued | 2013-01 | |
dc.description | Staff publications | en_US |
dc.description.abstract | Schiff bases of substituted salicylaldehydes namely 5-bromosalicylaldehyde and 5-nitrosalicyladehyde with 2- aminophenol and 2-aminothiophenol have been synthesized and characterized by IR, NMR and elemental analysis. All synthesized compounds were screened for their antimicrobial activity against some clinically important bacteria; Escherichia coli ATCC 25922, Pseudomonas aeruginosa ATCC 27853, Staphylococcus aureus ATCC25923, Enterococcus feacalis ATCC 29212 by Agar ditch method using N,N’-dimethylformamide (DMF) and 1,4-dioxane as solvents. Activity data shows a higher activity of the compounds in DMF with the bromo substituted imines more potent than the nitro substituted compounds | en_US |
dc.identifier.citation | Fasina, T.M, Elija, F.N & Dueke-Eze, C.U and Idika, N. (2013). Synthesis and Antimicrobial Activity of Schiff Bases Derived from Substituted Salicylaldehyde with 2-aminophenol and 2-aminothiophenol. Journal of Scientific Research and Development. Vol.14. 95-98pp. | en_US |
dc.identifier.uri | https://ir.unilag.edu.ng/handle/123456789/6032 | |
dc.language.iso | en | en_US |
dc.publisher | Journal of Scientific Research and Development | en_US |
dc.relation.ispartofseries | Journal of Scientific Research and Development;Vol.14 | |
dc.subject | 2-aminophenol | en_US |
dc.subject | 2-aminothiophenol | en_US |
dc.subject | Schiff base | en_US |
dc.subject | Antimicrobial activity | en_US |
dc.subject | Research Subject Categories::NATURAL SCIENCES::Chemistry | en_US |
dc.subject | Research Subject Categories::NATURAL SCIENCES::Chemistry | en_US |
dc.title | Synthesis and Antimicrobial Activity of Schiff Bases derived from substituted Salicyladehyde with 2-aminophenol and 2-aminothiophenol | en_US |
dc.type | Article | en_US |
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