Manganese(III)-mediated direct Csp2–H radical trifluoromethylation of coumarins with sodium trifluoromethanesulfinate
No Thumbnail Available
Date
2014-02-03
Authors
Cao, X.H.
Pan, X.
Zhou, P.J.
Zou, J.P.
Asekun, O.T.
Journal Title
Journal ISSN
Volume Title
Publisher
Royal society of chemistry
Abstract
Mn(OAc)3-mediated direct Csp2–H radical trifluoromethylation of coumarins with CF3SO2Na (Langlois reagent) to afford selective 3-trifluoromethyl coumarins in moderate to good yields is described. This methodology can also be applied to the trifluoromethylation of quinolinones and pyrimidinones.
Description
Keywords
Research Subject Categories::NATURAL SCIENCES::Chemistry::Organic chemistry::Organic synthesis , selective , trifluoromethylation , quinolinones , pyrimidinones
Citation
Cao, X. H., Pan, X., Zhou, P. J., Zou, J. P., & Asekun, O. T. (2014). Manganese (iii)-mediated direct C sp2–H radical trifluoromethylation of coumarins with sodium trifluoromethanesulfinate. Chemical communications, 50(25), 3359-3362.