Antioxidant activity of selected edible cucurbitaceous fruit peels

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dc.contributor.authorOiseoghaede, J.O.
dc.contributor.authorAjayi, G.
dc.contributor.authorAkinlotan, F.A.
dc.contributor.authorNwosu, I.C.
dc.contributor.authorBadmus, M.A.
dc.contributor.authorOluwasina, O.S.
dc.date.accessioned2019-11-29T15:39:36Z
dc.date.available2019-11-29T15:39:36Z
dc.date.issued2018-06-01
dc.descriptionStaff publicationsen_US
dc.description.abstractBackground: Peels of some edible fruits are regarded as waste and discarded. This study evaluated antioxidant activity of peels of selected cucurbitaceous fruits viz Cucumis melo Linn. var. inodorus (CM), Cucumis sativus Linn. (CS) and Citrullus lanatus (Thunb.) Matsum. & Nakai (CL) using standard in-vitro assays. The study also evaluated total flavonoid and phenolic contents of the extracts Methods: Oven dried peels were ground and then extracted with hydro-ethanol. Phytochemical screening and antioxidant activity of extracts was evaluated via hydrogen peroxide scavenging (HP), metal chelating (MC), ferric ion reducing (RC) capacity and 2,2-Diphenyl-1-picrylhydrazyl (DPPH) free radical scavenging assay methods. Total phenolic content and total flavonoid contents were also quantified. Results: Cucumis sativus extract showed significant metal chelating activity (p<0.05). Citrullus lanatus had significant metal chelating activity (p ≤ 0.05) at highest concentration of 0.1mg/ml with a higher peak activity, 58.47% when compared with the standard, Ethylenediaminetetraacetic acid (EDTA) 52.61%. Cucumis sativus at highest concentration (12.43% inhibition) showed significant Hydrogen peroxide radical scavenging activity (p ≤ 0.05). Low concentrations in three of the assays (HP, DPPH and RC), showed inferior activity (p ≤ 0.05). Antioxidant activity increased as extract concentration increased. The results showed that Cucumis melo had the highest phenolic contents while Cucumis sativus had the highest total flavonoids. Phytochemical screening revealed presence of tannins, flavonoids, terpenoids and sugars. Citrullus lanatus showed presence of deoxysugars. Conclusion: The peel extracts exhibited significant metal chelating and hydrogen peroxide radical scavenging activity. Continuous consumption of peels may offer additional health benefits stemming from better antioxidant with increased concentration. Hence, this health seeking diet should be encouraged.en_US
dc.identifier.citationOiseoghaede, J.O., Ajayi, G. O., Akinlotan, F.A., Nwosu, I.C., Badmus, M.A. and Oluwasina, O.S. (2018). Antioxidant activity of Selected Edible Cucurbitaceous Fruit Peels .The Nigerian Journal of Pharmacy, 52(1), pp. 28-36.en_US
dc.identifier.issn0331-670X
dc.identifier.urihttps://ir.unilag.edu.ng/handle/123456789/7024
dc.language.isoenen_US
dc.publisherPharmaceutical Society of Nigeriaen_US
dc.relation.ispartofseriesThe Nigerian Journal of Pharmacy;52(1)
dc.subjectAntioxidanten_US
dc.subjectCucumis sativusen_US
dc.subjectCucumis meloen_US
dc.subjectCucurbitaceaeen_US
dc.subjectResearch Subject Categories::PHARMACYen_US
dc.titleAntioxidant activity of selected edible cucurbitaceous fruit peelsen_US
dc.typeArticleen_US
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