Department of Biomedical Engineering
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Browsing Department of Biomedical Engineering by Author "Adeleye, O.A"
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- ItemOpen AccessAnalysis of convective-radiative porous fin With temperature-dependent internal heat Generation and magnetic field using Homotopy Perturbation(Journal of Computational and Applied Mechanics, 2017) Sobamowo, M.G; Adeleye, O.A; Yinusa, AIn this work, thermal behavior of convective-radiative porous fin with temperature-dependent internal heat generation subjected to magnetic field using homotopy perturbation method is analyzed. The developed symbolic heat transfer model is used to investigate the effects of convective, radiative, magnetic parameters on the thermal performance of the porous fin. From the study, it is established that increase in porosity, convective, radiative and magnetic parameters increase the rate of heat transfer from the fin and consequently, improve the efficiency of the fin. The homotopy perturbation method used in the work is validated with the results of a numerical method. The results of the two methods are in excellent agreement. Therefore, this study provides a platform for comparison of results of any other method of analysis of the problem. Also, such an analytical tool is valuable as a design and optimization approach for finned heat exchangers where each fin/row is analytically analyzed and where the surrounding fluid is influenced by a magnetic field.
- ItemOpen AccessApplication of a New Iterative Method To Analysis of Kinetics of Thermal Inactivation of Enzyme(U.P.B. Scientific Bulletin, 2018) Sobamowo, M.G; Adeleye, O.AIn this paper, a new iterative method proposed by Temimi and Ansari is applied to analyze the kinetic of thermal inactivation of jack bean urease (EC3.5.1.5). The analyzed kinetics or reaction mechanisms consist of three-reaction steps and included the Arrhenius equation for the temperature dependence of rate constants as well as the temperature change in the initial heating period. The obtained solutions are used to study the model parameters on the kinetics of thermal inactivation of enzyme. The analytical solutions are verified with numerical solutions using Runge – Kutta with shooting method and good agreements are established between the solutions. The information given in this theoretical investigation will assist in the kinetic analysis of the experimental results over handling rate constants and molar concentrations.
- ItemOpen AccessApplication of Daftardar-Gejiji and Jafari Method to Kinetic Analysis of Thermal Inactivation of Jack Bean Urease(Journal of Applied Mathematics and Computational Mechanics, 2018) Sobamowo, M.G; Adeleye, O.AJack bean urease has been used as a good catalyst for hydrolysis of urea in various applications such as biotechnology and biomedical engineering. The wide range of applications require proper understanding of the thermal inactivation of the enzyme. Consequently, the theoretical analysis of the enzyme kinetic of the thermal inactivation is required. In this paper, a new iterative method proposed by Daftardar-Gejiji and the Jafari method is applied to analyse the kinetic of thermal inactivation of jack bean urease (EC3.5.1.5). The kinetics of the urease consist of three-reaction steps and included the Arrhenius equation for temperature-dependent rate constants as well as the temperature change in the initial heating period. The approximate analytical solutions are verified with results of numerical method using Runge-Kutta with the shooting method, and good agreements are established between the results of the methods. From the analytical investigation, it is established that the molar concentration of the native enzyme decreases as the time increases while the molar concentration of the denatured enzyme increases as the time increases. The time taken to reach the maximum value of the molar concentration of the native enzyme is the same as the time taken to reach the minimum value of the molar concentration of the denature enzyme. It is hoped that the information given in this theoretical investigation will assist in the kinetic analysis of thermal inactivation of the experimental results over handling rate constants and molar concentrations.
- ItemOpen AccessDeformation Behavior of Led And Hiled Cured Dental Resin Microhybrid and Nanofilled Composites(UNILAG Journal of Medicine, Science and Technology, 2016) Adeleye, O.A; Fakinlede, O.A; Ajiboye, J.S; Adegbulugbe, C.IThe deformation behavior of commercial microhybrid resin based composite (20/20 composite) and nanofilled composite (Light Cured Universal Composite) cured with the conventional Light Emitting Diode (LED) and exponential Light Emitting Diode (HiLED) under various loading condition have been investigated. Deformation of restorations such as shrinkage and shearing from curing and mastication have been a major concern for clinicians because of void and crack formations in restored tooth structure which affects the mechanical properties of the resin composites. Samples of microhybrid resin based composite (20/20 composite) and nanofilled composite (Light Cured Universal Composite) were molded with copper foil molds with standard dimension 2 x 2.5 x 8mm, photo-cured by both conventional Light Emitting Diode (LED) and exponential Light Emitting Diode (HiLED) and then tested on the ElectroForce 3200 for their deformation behavior and mechanical properties. Effects of variation of strain rate and curing time were also investigated. The results showed that, out of the four groups of samples studied, microhybrid resin based composite (20/20 composite) cured with exponential Light Emitting Diode (HiLED) exhibited highest tensile strength of 28 MPa. The loading and unloading of the samples exhibited hysteresis responses and path dependence nonlinear behavior. At stress values less than 4 MPa, rate dependent recoverable (viscoelasticity) deformation was observed in all the four groups of samples but at stress values beyond 4 MPa rate dependent irrecoverable (viscoplasticity) deformation was observed. Finally, it was observed that increasing curing time leads to increasing tensile strength for materials cured by both methods.
- ItemOpen AccessDevelopment of Exact Analytical Solution for Nonlinear Heat transfer Equation of Natural Convection Porous Fin(Journal of Engineering Research, 2016) Sobamowo, M.G; Adeleye, O.AThe present of nonlinear term in heat transfer models makes it very difficult to develop exact analytical solutions to the problem. Consequently, recourse has been made to numerical or approximate analytical methods. However, the classical way for finding exact analytical solution is obviously still very important since it serves as an accurate benchmark for numerical and approximate analytical solutions. Therefore, in this work, exact analytical solution is developed using Gauss’ hypergeometric function for the nonlinear equation arising during heat transfer in porous fin. The developed model was validated with numerical method of solutions and the results were in good agreement. The developed exact analytical model can be compared with other approximate analytical methods found in the literature which are used for solving similar problems.
- ItemOpen AccessDynamic Analysis of the Biomechanical Model of Head Load Impact Using Differential Transform Method(Journal of Applied and Computational Mechanics JACM,, 2019) Adeleye, O.A; Ipinnimo, O; Yinusa, A.A; Otobo, E.PThe dynamic analysis of the biomechanical model of the head load impact using the Differential Transform Method is presented in this paper. In many parts of the world, the problem of traumatic brain injuries (TBI) has led to neurodegenerative dementing disorders and diseases as a result of head load impact from sporting activities, accidents involving the head, etc. have serious effects on humanity. The head load impact and its control have been modeled as a rigid linkage head-neck manipulator. This rigid link manipulator is governed by a system of nonlinear ordinary differential matrix equations with three degrees of freedom which requires special techniques for its solution. The system of equations was solved using Differential Transform Method (DTM) and the results were compared with results obtained in earlier studies and validated with the fourth-order Runge-Kutta numerical method (RK4). Good agreements are reached in all these results. From the model, the effects of head loads, head mass, neck mass, upper and lower linkage lengths, head and neck moments of inertia were investigated. As the head loads increased, there were increases in both axial and angular displacement of the head motion and the neck region. The study provides a theoretical basis for the design and understanding of the effects of head load carriage on vital organs that are susceptible to pains, damages, and even failure.
- ItemOpen AccessThe Effects of Resin Matrix Composition, Filler Volume And Particle Size On The Mechanical Properties Of Dental Resin Composites(UNILAG Journal of Medicine, Science and Technology, 2016) Adeleye, O.A; Fakinlede, O.A; Makinde, J.TThe behaviour of dental resin composites (DRC’s) under mechanical loading has been of concern in dentistry as it determines their clinical application. The aim of this study is therefore to check the effect of the resin matrix composition, filler volume and particle size on the mechanical properties of DRC’s. In this experimental in-vitro study, six types of composite resins were used as follows:Two(2) Micro hybrid- Super Cor (SC) and Natural look(NL); Two(2) hybrid- Alpha dent (AD) and Henry Schein (HS) and two(2) Nano hybrid- i-Xcite(IX) and Fusion(FS),each with varying resin matrix composition, filler volume and particle size. Samples were prepared in aluminum molds and light cured using Optilight Max GNATUS light curing unit at constant time intervals of 20 seconds as specified in literature and designed by curing light manufacturers. The specimens were stored in distilled water at 37°C for 48 hours. Subsequently, the specimens were subjected to tensile test and three point loading using the BOSE Electro Force 3200 system at cross head speed of 1.0mm/min and varying speed of 0.5, 2.0 and 5.0mm/min. Henry Schein 20/20 (hybrid; bis-GMA; 56%) exhibited flexural strength of 17MPa but tensile strength of 29.7MPa amongst the group. i-Xcite (nanohybrid; bis-GMA,TEGDMA,UDMA;76.5%) showed the flexural strength of 138MPa and relatively low tensile strength of 25.3MPa. All resin types showed increasing flexural strength with increasing strain rate. Tensile and Flexural strength are dependent on the resin matrix composition, the filler particle size and then the filler volume in that order.
- ItemOpen AccessFurther Study on Thermal Performance of Porous Fin with Temperature-Dependent Thermal Conductivity and Internal Heat Generation using Galerkin’s method of Weighted Residual(World Scientific News, WSN, 2019) Sobamowo, M.G; Kamiyo, O.M; Adeleye, O.AThis work is presented as a further study to our previous work, “Thermal performance analysis of a natural convection porous fin with temperature-dependent thermal conductivity and internal heat" published in "Thermal Science and Engineering Progress. 1 (2017) 39–52”, where it was assumed that the surface convection is negligible and heat is transferred only by natural convection in the porous fin. In this present study, such an assumption has been relaxed. Also, effects of surface convective heat transfer on the thermal performance of porous fin with temperature-dependent thermal conductivity and internal heat generation have been investigated using Galerkin’s method of weighted residual. The results of the Galerkin’s method of weighted residual show excellent agreement with the results of numerical method using shooting method coupled with Runge-Kutta method and also with the results of homotopy perturbation method. Thereafter, the developed analytical solutions are used to investigate the influences of the thermal model parameters on the thermal performance of the porous fin. It is found as the with the other model parameters that as the convective parameter increases, the rate of heat transfer from the base of the fin increases and consequently, the porous fin efficiency improves. However, increase in the nonlinear thermal conductivity parameter decreases the temperature distribution in the fin. Based on the high accuracy of the Galerkin’s method of weighted residual as displayed in this work, it is hoped that the simple analytical solutions given by the approximate analytical method will enhance the analysis of extended surfaces and also assist the designers.
- ItemOpen AccessHeat Transfer Analysis of Non-Newtonian Natural Convective Fluid Flow Using Homotopy Perturbation and Daftardar-Gejiji & Jafari Methods(Journal of Applied Mathematics and Computational Mechanics, 2019-07) Adeleye, O.A; Ahmed, YIn this paper, the analytical solution of natural convective heat transfer of a non-Newtonian fluid flow between two vertical infinite plates using the Homotopy Perturbation Method (HPM) and Daftardar-Gejiji & Jafari Method (DJM) is presented. The heat transfer problem of natural convection is observed in many engineering fields including geothermal systems, heat exchangers, petroleum reservoirs, nuclear waste reserves, etc. The problem which is modelled as fully coupled nonlinear ordinary differential equations requires special analytical techniques for its solution. The solutions are obtained using an exact analytical method: the Homotopy Perturbation Method (HPM) and a semi-analytical method: the Daftardar-Gejiji & Jafari Method (DJM). These solutions are compared with solutions obtained from the Runge-Kutta numerical method. The results are in good agreement with the numerical solutions. The effects of the Eckert number, Prandtl number and the non-Newtonian fluid viscosity parameter on the non-dimensional temperature and velocity of the fluid are investigated. The results obtained from the analytical method show that the method can be applied to predict excellent results of the problem and can be used for parametric studies of the problem. From the results, it is shown that when the Prandtl number and the Eckert number are increased, there is an increase in both temperature and fluid flow velocity.
- ItemOpen AccessHeat Transfer And Flow Analysis Of Magnetohydrodynamic Dissipative Carreau Nanofluid Over A Stretching Sheet With Internal Heat Generation(Journal of Computational and Engineering Mathematics, 2019) Sobamowo, M.G; Adeleye, O.A; Yinusa, A.AThe unsteady two-dimensional flow and heat transfer analysis of Carreau nanofluid over a stretching sheet subjected to magnetic field, temperature dependent heat source/sink and viscous dissipation is presented in this paper. Similarity transformations are used to reduce the systems of the developed governing partial differential equations to nonlinear third and second orders ordinary differential equation which are solved using differential transform method. Using kerosene as the base fluid embedded with the silver (Ag) and copper (Cu) nanoparticles, the effects of pertinent parameters on reduced Nusselt number, flow and heat transfer characteristics of the nanofluid are investigated and discussed. From the results, it is established temperature field and the thermal boundary layers of Ag-Kerosene nanofluid are highly effective when compared with the Cu-Kerosene nanofluid. Heat transfer rate is enhanced by increasing in power-law index and unsteadiness parameter. Skin friction coefficient and local Nusselt number can be reduced by magnetic field parameter and they can be enhanced by increasing the aligned angle. Friction factor is depreciated and the rate of heat transfer increases by increasing the Weissenberg number. Also, for the purpose of verification, the results of the analytical of the approximate analytical solutions are compared with the results of numerical solution using Runge-Kutta coupled with Newton method. A very good agreement is established between the results. This analysis can help in expanding the understanding of the thermo-fluidic behaviour of the Carreau nanofluid over a stretching sheet.
- ItemOpen AccessHomotopy Perturbation Method For Kinetic Analysis Of Thermal Inactivation Of Jack Bean Urease(Karbala International Journal of Modern Science, 2018) Sobamowo, M.G; Adeleye, O.AIn this work, theoretical modeling and determination of molar concentration of the native and denatured jack bean urease (EC 3.5.1.5) are presented. A three-reaction kinetic model of thermal inactivation of urease is analyzed using homotopy perturbation method. The obtained analytical solutions are used to study the kinetics of thermal inactivation of the enzyme as applied in biotechnology. From the results, it is established that the molar concentration of native enzyme decreases as the time increases while the molar concentration of the denatured enzyme increases as the time increases. The time taken to reach the maximum value of the molar concentration of native enzyme is the same as the time taken to reach the minimum value of the molar concentration of the denature enzyme. The molar concentration of the denatured enzyme reaches the steady state value when reaction time is less than or equal to 5s. Also, the molar concentration of the denatured enzyme becomes zero when rate constant of dissociation reaction of the native form of the enzyme into a denatured form, is less than or equal to 0.01 s 1. The analytical solutions are verified with numerical solutions using Runge Kutta with shooting method and good agreements are established between the solutions. The information given in this theoretical investigation will assist in the kinetic analysis of the experimental results over handling rate constants and molar concentrations.
- ItemOpen AccessInfluences on Flexural Strength And Deformation Behavior of Led Cured Microhybrid And Nanofilled Dental Resin Composites(2015 Biomedical Engineering Society Annual Meeting, 2015, Tampa, Florida, United States, 2015) Osuntoki, A.A; Ajibola, O.O.E; Adeleye, O.A; Fakinlede, O.A; Adegbulugbe, C.IA major modern application of engineering materials is to support biological tissues. Mechanical tests that closely simulate the real world activity on these materials are the most reliable way of predicting their service performance under load bearing activity. Flexural strength is an important property for characterizing brittle materials because the test generates complex tensions by combining tensile stress, compression and shear. In general, high flexural strength is desired for restorative materials that support the occlusal forces of posterior teeth. Several factors such as curing time and strain rates as well as the constituents of the dental resin composites affect the flexural strength. Deformation behaviour of restorations, such as shrinkage and shearing from curing and mastication, have also been a major concern for clinicians because of void and crack formations in restored tooth structure which affects the mechanical properties of the resin composites.
- ItemOpen AccessKinetics Analysis of Thermal Inactivation of Enzyme used in Biotechnology using Variation Iteration Method(Annals of the Faculty of Engineering Hunedoara, 2018) Sobamowo, M.G; Adeleye, O.AIn this work, variation iteration method is used to develop analytical solutions for the prediction of molar concentration of native and denatured jack bean urease (EC 3.5.1.5) through the three–reaction steps kinetic model of thermal inactivation of the urease. The obtained analytical solutions are used to study the kinetics of thermal inactivation of the enzyme as applied in biotechnology. The analytical solutions are verified with numerical solutions using Runge–Kutta with shooting method and good agreements are established between the solutions. The information given in this theoretical investigation will assist in the kinetic analysis of the experimental results over handling rate constants and molar concentrations. The analytical solutions as developed in this work can serve as a starting point for a better understanding of the relationship between the physical quantities of the problems.
- ItemOpen AccessNonlinear Vibrations of Single‑ and Double‑Walled Carbon Nanotubes Resting on Two‑Parameter Foundation in a Magneto‑Thermal Environment(Springer Nature Applied Sciences, (SNAS), 2019) Sobamowo, M.G; Akanmu, J.O; Adeleye, O.A; Yinusa, A.AThe excellent mechanical, electrical, structural and thermal properties coupled with high strength to weight ratio of carbon nanotubes have tremendously expanded their applications in various industrial, engineering, physical and natural sciences processes. In this work, nonlocal elasticity theory is used to analyze nonlinear vibrations of single and double walled carbon nanotubes resting on two-parameter foundation in a thermal and magnetic environment. With the aid of Galerkin decomposition method, the systems of nonlinear partial differential equations are transformed into systems of nonlinear ordinary differential equations which are solved using homotopy perturbation method. The developed analytical solutions are used to investigate the influences of elastic foundations, magnetic field, temperature rise, interlayer forces, small scale parameter and boundary conditions on the frequency ratio. From the results, it is observed that the frequency ratio for all boundary conditions decreases as the number of walls increases from single to double. Also, it is established that the frequency ratio is highest for clamped–simple supported and lowest for clamped–clamped supported. Additionally, the results revealed that the frequency ratio decreases with an increase in the value of spring constant (k1) temperature and magnetic field strength. This work will enhance the applications of carbon nanotubes in structural, electrical, mechanical and biological applications, especially in a thermal and magnetic environment.
- ItemOpen AccessNonlinear Vibrations of Single‑ and Double‑Walled Carbon Nanotubes Resting on Two‑Parameter Foundation in a Magneto‑Thermal Environment(Springer Nature Applied Sciences, (SNAS), 2019) Sobamowo, M.G; Akanmu, J.O; Adeleye, O.A; Yinusa, A.AThe excellent mechanical, electrical, structural and thermal properties coupled with high strength to weight ratio of carbon nanotubes have tremendously expanded their applications in various industrial, engineering, physical and natural sciences processes. In this work, nonlocal elasticity theory is used to analyze nonlinear vibrations of single and doublewalled carbon nanotubes resting on two-parameter foundation in a thermal and magnetic environment. With the aid of Galerkin decomposition method, the systems of nonlinear partial differential equations are transformed into systems of nonlinear ordinary differential equations which are solved using homotopy perturbation method. The developed analytical solutions are used to investigate the influences of elastic foundations, magnetic field, temperature rise, interlayer forces, small scale parameter and boundary conditions on the frequency ratio. From the results, it is observed that the frequency ratio for all boundary conditions decreases as the number of walls increases from single to double. Also, it is established that the frequency ratio is highest for clamped–simple supported and lowest for clamped–clamped supported. Additionally, the results revealed that the frequency ratio decreases with increase in the value of spring constant (k1) temperature and magnetic field strength. This work will enhance the applications of carbon nanotubes in structural, electrical, mechanical and biological applications especially in a thermal and magnetic environment.
- ItemOpen AccessPicard Iteration Method to Kinetic Analysis of Thermal Inactivation of Enzyme as Applied in Biotechnology(International Journal of Advanced Design and Manufacturing Technology, 2018) Adeleye, O.A; Sobamowo, M.GIn this work, Picard iteration method is used to obtain analytical expressions for the prediction of molar concentration of native and denatured jack bean urease (EC 3.5.1.5) through the three-reaction steps kinetic model of thermal inactivation of the urease. The obtained solutions are used to study the kinetics of thermal inactivation of the enzyme as applied in biotechnology. The analytical solutions are verified with numerical solutions using Runge –Kutta with shooting method and good agreements are established between the solutions. From the parametric studies using the iterative method, the molar concentration of native enzyme decreases as the time increases while the molar concentration of the denatured enzyme increases as the time increases. The time taken to reach the maximum value of the molar concentration of native enzyme is the same as the time taken to reach the minimum value of the molar concentration of the denature enzyme. The information given in this theoretical investigation will assist in the kinetic analysis of the experimental results over handling rate constants and molar concentrations
- ItemOpen AccessPredictions of Creep Strain Relaxations in Biomaterials Using Differential Transform Method(Journal of Biomimetics, Biomaterials and Biomedical Engineering, 2018) Adeleye, O.A; Eloka, A.; Sobamowo, M.GThe complexity of the multiple interactive reactions of various cells/proteins and biochemical processes during phagocyte transmigration for foreign body responses to subcutaneous biomaterial implants have been studied through developed kinetics-based predictive models which have been numerically analyzed. However, the need for direct relationship between the kinetic based predictive models parameters and the requirements for continuous insights into the significance of various process parameters affecting the phenomena have led to the quest for developing analytical solutions. Therefore, in this work, differential transform method is used to develop analytical solutions for the prediction of phagocyte transmigration for foreign body responses to subcutaneous biomaterial implants. The approximate analytical solutions are used to study the effect of various model parameters on phagocyte transmigration to foreign body responses in biomaterial implantation. The results of the analytical solutions are agreement with the results of the previous studies.
- ItemOpen AccessPredictions of Phagocyte Transmigration for Foreign Body Response during Biomaterial Implantation Using Differential Transform Method(Journal of Biomimetics, Biomaterials and Biomedical Engineering, 2017) Adeleye, O.A; Olawale, O.; Sobamowo, M.GThe complexity of the multiple interactive reactions of various cells/proteins and biochemical processes during phagocyte transmigration for foreign body responses to subcutaneous biomaterial implants have been studied through developed kinetics-based predictive models which have been numerically analyzed. However, the need for direct relationship between the kinetic based predictive models parameters and the requirements for continuous insights into the significance of various process parameters affecting the phenomena have led to the quest for developing analytical solutions. Therefore, in this work, differential transform method is used to develop analytical solutions for the prediction of phagocyte transmigration for foreign body responses to subcutaneous biomaterial implants. The approximate analytical solutions are used to study the effect of various model parameters on phagocyte transmigration to foreign body responses in biomaterial implantation. The results of the analytical solutions are agreement with the results of the previous studies.
- ItemOpen AccessA Study On Effects Of Wall Slip Condition And Magnetic Field On Squeezing Axisymmetric Flow Of First-Grade Nanofluid Through A Porous Medium(ANNALS of Faculty Engineering Hunedoara – International Journal of Engineering, 2018) Sobamowo, M,G; Popoola, O,P; Adeleye, O.AThe influences of wall slip condition and magnetic field on steady two-dimensional axisymmetric squeezing flow of nanofluid through a porous medium are studied using homotopy perturbation method. The approximate analytical method used in this work is verified by comparing the results of the approximate analytical method with the results of numerical method using Runge-Kutta coupled with shooting method. Thereafter, the analytical solution is used to carry out parametric studies of the flow process. The results show that the velocity of the fluid increases with increase in the magnetic parameter under slip condition while the velocity of the fluid decreases with increase in the magnetic field parameter under the no slip condition. By increasing the slip parameter, the velocity of the fluid increases and the fluid velocity decrease as the Reynolds number increases. This study is useful in the flow analysis of fluid such as found in biological and engineering applications.
- ItemOpen AccessSymbolic Analysis of Heat Transfer in Radial Fin(Journal of Engineering Research, 2010) Adeleye, O.A; Fakinlede, O.AIn this paper, a novel application domain of the symbolic implementation of finite element method using a linear heat dissipation radial fin has been presented. The problem of temperature distribution and heat transfer in radial fins of triangular, rectangular and parametric profiles was modeled and validated using symbolic computation. The current study has shown that the symbolic computational technique is less complex, effective and efficient in comparison with the earlier techniques used to solve heat transfer problem in this same problem domain. Our proposed concept could be adapted to solving heat transfer problems in further extended surfaces.